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New treatment option for Dyspepsia and Other Specified Disorders of Function of Stomach
Official title Holy Basil in The Treatment of Dyspepsia
ClinicalTrials.gov ID: NCT07175272
What this study is testing
What is Holy basil extract?
Holy basil extract is an investigational medicine, given as an once-weekly pill taken by mouth, being studied as a potential treatment for dyspepsia and other specified disorders of function of stomach.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to evaluate whether holy basil extract can reduce gastric inflammation and improve symptoms in adult patients with dyspepsia. The main questions it aims to answer are: Does holy basil extract reduce gastric mucosal inflammation as measured by histopathology?
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Participants aged 18 years and older.
- Presence of dyspeptic symptoms, assessed by the Leeds Dyspepsia Questionnaire with a score of at least 5 or higher.
You likely can't join if
- Presence of Helicobacter pylori infection.
- Diagnosis of peptic ulcer or erosive esophagitis Los Angeles Classification grade B or greater.
- Use of acid-suppressant therapy including proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) that cannot be discontinued at...
- Use of mucosal protective agents, such as rebamipide, sucralfate, or irsogladine that cannot be discontinued at least 4 weeks prior enrolment and...
- History of gastric cancer or duodenal cancer.
- Previous upper gastrointestinal surgery.
See the full eligibility criteria
- Participants aged 18 years and older.
- Presence of dyspeptic symptoms, assessed by the Leeds Dyspepsia Questionnaire with a score of at least 5 or higher.
- Presence of Helicobacter pylori infection.
- Diagnosis of peptic ulcer or erosive esophagitis Los Angeles Classification grade B or greater.
- Use of acid-suppressant therapy including proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) that cannot be discontinued at least 2 weeks prior enrolment and during the study period.
- Use of mucosal protective agents, such as rebamipide, sucralfate, or irsogladine that cannot be discontinued at least 4 weeks prior enrolment and during the study period.
- History of gastric cancer or duodenal cancer.
- Previous upper gastrointestinal surgery.
- Current pregnancy or lactation.
- Known allergic to the medicine.
The study team makes the final eligibility decision.
Where it's taking place
- Bangkok Noi, Bangkok, Thailand
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bangkok Noi, Bangkok, Thailand. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.