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New treatment option for Cardiac Surgery
Official title Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac Surgery
ClinicalTrials.gov ID: NCT07164677
What this study is testing
What is IV morphine patient-controlled analgesia?
IV morphine patient-controlled analgesia is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for cardiac surgery.
Also referred to as morphine PCA.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this study is to investigate the efficacy of bilateral serratus posterior superior intercostal plane (SPSIP) block on postoperative acute pain and opioid consumption in patients undergoing on-pump open-heart surgery. Postoperative outcomes including pain scores, cumulative morphine use, quality of recovery, and opioid-related side effects will be evaluated within the first 24 hours after surgery.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Patients aged 18-80 undergoing elective on-pump open-heart surgery via median sternotomy.
- American Society of Anesthesiologists (ASA) classification II-III patients.
- Patients who can use PCA.
- Patients who will sign the informed consent form.
You likely can't join if
- History of opioid use for more than four weeks
- Chronic pain syndromes
- Patients with a history of local anesthetic or opioid allergy, hypersensitivity
- Alcohol and drug addiction
- Conditions where regional anesthesia is contraindicated
- Failure in the dermatomal examination performed after the block
See the full eligibility criteria
- Patients aged 18-80 undergoing elective on-pump open-heart surgery via median sternotomy.
- American Society of Anesthesiologists (ASA) classification II-III patients.
- Patients who can use PCA.
- Patients who will sign the informed consent form.
- History of opioid use for more than four weeks
- Chronic pain syndromes
- Patients with a history of local anesthetic or opioid allergy, hypersensitivity
- Alcohol and drug addiction
- Conditions where regional anesthesia is contraindicated
- Failure in the dermatomal examination performed after the block
- Emergency surgeries and redo surgeries.
- Individuals with obstructive sleep apnea.
- Left ventricular ejection fraction less than 30%.
- Patients with severe psychiatric illnesses (such as psychosis, dementia) that limit cooperation with verbal numerical pain scales.
- Pregnant and breastfeeding patients.
- Hematological disorders.
- Significant impairment in the function of a major organ (e.g., severe hepatic or renal disease). Patients who cannot be extubated within the first 6 hours postoperatively.
The study team makes the final eligibility decision.
Where it's taking place
- Samsun, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Samsun, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.