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New treatment option for Blood Coagulation Disorder
Official title Comparative Study of Tranexamic Acid Dosing in Cardiac Surgery
ClinicalTrials.gov ID: NCT07164300
What this study is testing
What is Tranexamic acid at a dose of 10 mg/kg followed by 1 mg/kg/h?
Tranexamic acid at a dose of 10 mg/kg followed by 1 mg/kg/h is an investigational medicine, being studied as a potential treatment for blood coagulation disorder.
Also referred to as Group 1.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Tranexamic axid is routinely used as an antifibrinolytic agent in cardiac surgery to reduce the risk of blood loss and transfusion. However, there is no consensus regarding the dosage regimen of tranexamic acid that should be administered.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 99
You may be able to join if
- Patients undergoing elective cardiac surgery using cardiopulmonary bypass
- Patients to have discontinued anticoagulant and antiplatelet therapy preoperatively according to guidelines.
You likely can't join if
- Age below 18 years
- Patient refusal
- Pregnancy
- End-stage renal disease
- History of epilepsy,
- Cardiac surgery without the use of cardiopulmonary bypass (off-pump)
See the full eligibility criteria
- Patients undergoing elective cardiac surgery using cardiopulmonary bypass
- Patients to have discontinued anticoagulant and antiplatelet therapy preoperatively according to guidelines.
- Age below 18 years
- Patient refusal
- Pregnancy
- End-stage renal disease
- History of epilepsy,
- Cardiac surgery without the use of cardiopulmonary bypass (off-pump)
- Emergency operations
- Known allergy to the administered agents.
The study team makes the final eligibility decision.
Where it's taking place
- Ioannina, Greece
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ioannina, Greece. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.