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New treatment option for Solid Tumours
Official title A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors
ClinicalTrials.gov ID: NCT07160725
What this study is testing
What is BMS-986517?
BMS-986517 is an investigational medicine, being studied as a potential treatment for solid tumours.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- A phase 1/2a, open-label, first-in-human study mainly aimed to evaluate the safety and tolerability of BMS-986517 in participants with solid tumors
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Participants must have an ECOG performance status of 0 to 1.
- Participants must have measurable disease by RECIST v1.1 (radiologically measured by the Investigator).
- Participants must have documented histologically or cytologically confirmed advanced, unresectable/metastatic solid tumors, including NSCLC, HNSCC...
You likely can't join if
- Participants must not have untreated CNS metastases. Participants are eligible if CNS metastases have been treated and do not require immediate...
- Participants must not have concurrent malignancy (present during Screening) requiring treatment or history of prior malignancy active within 2 years...
- Participants must not have history of serious recurrent infections.
- Participants must not have impaired cardiac function or history of severe heart disease.
- Other protocol-defined inclusion/exclusion criteria apply.
The study team makes the final eligibility decision.
Where it's taking place
- Irvine, California, United States
- Los Angeles, California, United States
- Orange, California, United States
- Pittsburgh, Pennsylvania, United States
- Sioux Falls, South Dakota, United States
- Fort Worth, Texas, United States
- San Antonio, Texas, United States
- West Valley City, Utah, United States
- Seattle, Washington, United States
- Copenhagen, Capital Region, Denmark
- Odense, Region Syddanmark, Denmark
- Copenhagen, Denmark
- Chuo-ku, Tokyo, Japan
- Málaga, Andalusia, Spain
- Badalona, Barcelona [Barcelona], Spain
- Barcelona, Barcelona [Barcelona], Spain
- Pamplona, Navarre, Spain
- Madrid, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Irvine, California, United States; Los Angeles, California, United States; Orange, California, United States; Pittsburgh, Pennsylvania, United States; Sioux Falls, South Dakota, United States; Fort Worth, Texas, United States and 12 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.