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New treatment option for Hidradenitis Suppurativa (HS)
Official title 1726-nm Laser for Acne Inversa (Hidradenitis Suppurativa)
ClinicalTrials.gov ID: NCT07155239
What this study is testing
- What it's testing
- Hidradenitis suppurativa (HS) is a long-lasting skin condition that causes painful lumps, abscesses, and tunnels in areas such as the armpits and groin. HS begins around the hair follicle; when the follicle becomes blocked and inflamed, new lesions form.
- Phase 1: an early, usually small safety study
- Time commitment: about 8 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Adults 18-60 years; any sex; Fitzpatrick I-VI.
- Clinical HS, Hurley I-II (Investigator confirmed).
- At least one inflammatory nodule in a paired, bilateral region (axilla, groin/inguinal, inframammary, inner thigh, or buttock) within 4 weeks prior...
- Able to read/speak English/Chinese/Spanish/Vietnamese and sign consent.
- Willing/able to comply with visits, pre/post-care, standardized photography.
You likely can't join if
- Hurley III (extensive sinus tracts).
- No qualifying nodule(s) in paired bilateral regions in past 4 weeks.
- Prior device/procedure to target areas within 3 months (chemical peel, dermabrasion, microneedling/RF, other lasers/LBB, cryo/chemo-destruction)
- Had Botulinum toxin in target areas within 3 months or planned during study.
- Had systemic retinoid (e.g., isotretinoin) within 3 months.
- Photosensitizing meds that, in PI's judgment, materially increase risk and cannot be held.
See the full eligibility criteria
- Adults 18-60 years; any sex; Fitzpatrick I-VI.
- Clinical HS, Hurley I-II (Investigator confirmed).
- At least one inflammatory nodule in a paired, bilateral region (axilla, groin/inguinal, inframammary, inner thigh, or buttock) within 4 weeks prior to baseline.
- Able to read/speak English/Chinese/Spanish/Vietnamese and sign consent.
- Willing/able to comply with visits, pre/post-care, standardized photography.
- Agree to avoid new HS procedures/therapies in study areas through Week 24.
- No laser contraindication; agrees to shave/clip hair before treatments.
- Optional translational cohort: willing to undergo 4-mm punch biopsy at baseline and Week 16 from the assigned by chance regions (separate consent).
- Hurley III (extensive sinus tracts).
- No qualifying nodule(s) in paired bilateral regions in past 4 weeks.
- Prior device/procedure to target areas within 3 months (chemical peel, dermabrasion, microneedling/RF, other lasers/LBB, cryo/chemo-destruction)
- Had Botulinum toxin in target areas within 3 months or planned during study.
- Had systemic retinoid (e.g., isotretinoin) within 3 months.
- Photosensitizing meds that, in PI's judgment, materially increase risk and cannot be held.
- Pregnancy/breastfeeding/plans to conceive during study.
- Active infection, still healing wounds (investigator judgment) in target areas.
- History of keloids/hypertrophic scars, radiation to target areas, malignancy in target areas, diagnosed immunodeficiency, uncontrolled coagulation disorder or therapeutic anticoagulation that cannot be safely managed.
- Excessive tanning or inability to avoid tanning.
- Any condition (medical/mental) or prisoner status that in PI's opinion compromises safety or adherence.
The study team makes the final eligibility decision.
Where it's taking place
- Rosemead, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 8 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rosemead, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.