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New treatment option for Aphasia Following Cerebral Infarction
Official title Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia
ClinicalTrials.gov ID: NCT07151677
What this study is testing
- What it's testing
- The goal of this clinical trial is to determine if electrical brain stimulation applied to the front parts of the brain can help people who have had a stroke improve their fatigue, language, and attention. The main question it aims to answer is: Does transcranial direct current stimulation (tDCS) administered to the pre-frontal areas of the brain improve post-stroke fatigue and aphasia?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 18 years or older.
- No diagnosis of neurological disorder (other than stroke).
- No diagnosis of psychiatric disorder, with the exception of anxiety and/or depression if it is managed through medication and/or behavioral...
- No seizure within the past 6 months.
- Not pregnant.
You likely can't join if
- Younger than 18 years old.
- Diagnosis or history of neurological disorder other than stroke.
- Diagnosis or history of psychiatric disorder with the exception of anxiety and/or depression if it is managed through medication and/or behavioral...
- History of seizures within the past 6 months.
- Pregnant.
- Currently has cardiac pacemaker
See the full eligibility criteria
- 18 years or older.
- No diagnosis of neurological disorder (other than stroke).
- No diagnosis of psychiatric disorder, with the exception of anxiety and/or depression if it is managed through medication and/or behavioral intervention.
- No seizure within the past 6 months.
- Not pregnant.
- Does not currently have cardiac pacemaker
- In chronic phase of recovery, defined as at least 6 months post-stroke.
- Not undergoing speech and language therapy targeting auditory comprehension or attention for the duration of the study.
- No metal implants in the scalp or bone in the pre-frontal area of the head.
- No unhealed skull fractures.
- Onset of aphasia related to single, left hemisphere, ischemic stroke.
- Damaged brain tissue from stroke does not overlap with left hemisphere dorsolateral prefrontal cortex.
- Mild to moderate aphasia (as measured by WAB-R \ \ or QAB).
- Self-report of post-stroke fatigue (as measured on SF-CAT)
- No significant challenges with vision or hearing (with use of corrective aids if needed; eyeglasses, hearing aids).
- Willing to allow audio-recording of study sessions.
- Younger than 18 years old.
- Diagnosis or history of neurological disorder other than stroke.
- Diagnosis or history of psychiatric disorder with the exception of anxiety and/or depression if it is managed through medication and/or behavioral intervention.
- History of seizures within the past 6 months.
- Pregnant.
- Currently has cardiac pacemaker
- \<6 months post-stroke (however, if this is only exclusionary criterion met, participant can be re-evaluated at the 6-month mark if still interested in the study)
- Currently undergoing speech and language therapy targeting auditory comprehension or attention.
- Metal implants in the scalp or bone in the pre-frontal area of the head.
- Currently has an unhealed skull fracture.
- Onset of aphasia related to etiology other than ischemic left hemisphere stroke.
- Damaged brain tissue significantly overlaps with left hemisphere dorsolateral prefrontal cortex.
- No aphasia or severe aphasia (as measured by WAB-R \ \ or QAB).
- Does not report experience of post-stroke fatigue (as measured on SF-CAT)
- Significant challenges with vision and/or hearing (even with use of corrective aids).
- Unwilling to allow audio-recording of study sessions.
The study team makes the final eligibility decision.
Where it's taking place
- Ann Arbor, Michigan, United States
- Syracuse, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ann Arbor, Michigan, United States; Syracuse, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.