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New treatment option for RA
Official title PET-Based Imaging of Radiolabeled CIT-013
ClinicalTrials.gov ID: NCT07147959
What this study is testing
What is [89Zr]Zr-CIT?
[89Zr]Zr-CIT is an investigational medicine, being studied as a potential treatment for ra.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Inflammatory mediated immune diseases (IMIDs), such as rheumatoid arthritis (RA) and hidradenitis suppurativa (HS), are characterized by chronic inflammation resulting from an aberrant immune response. Recent studies have identified neutrophil extracellular traps (NETs) as key contributors to the pathology of these diseases.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 85
You may be able to join if
- Female (of non-childbearing potential) or male between 60-85 years of age (both inclusive).
- For male participants with female partners of child-bearing potential, an adequate form of contraception must be adhered to, and men must refrain...
- Willing and able to provide written, informed consent.
You likely can't join if
- Diagnosed with RA according to the 2010 classification criteria of the American College of Rheumatology (ACR) and the European League Against...
- Participants in Cohort A (active RA) must furthermore meet the following criteria:
- \- Disease Activity Score 28 (DAS28) C-Reactive Protein (CRP) (DAS28-CRP) ≥ 4.2 AND ≥ 1 Swollen Joint AND ≥ 1 Tender Joint prior to screening.
The study team makes the final eligibility decision.
Where it's taking place
- Nijmegen, Netherlands
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nijmegen, Netherlands. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.