BridgeMD
New treatment option for Hyperuricemia With or Without Gout
Official title The Effects of a Probiotic Food Supplement in Hyperuricaemia
ClinicalTrials.gov ID: NCT07141888
What this study is testing
- What it's testing
- The overall aim of the project is to determine whether a daily intake of health-promoting bacteria, known as probiotics, with or without a dietary fiber, affects uric acid levels in individuals with elevated levels of uric acid in the blood (hyperuricemia). Additionally, the project will investigate which individuals benefit from this dietary supplement and which do not, based on factors such as gut microbiota composition and function, dietary habits, genetic factors, and inflammatory status.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Signed informed consent prior to any study-related procedures
- Age 18-80 years old
- BMI range 17.5-40 kg/m2
- Blood uric acid above 405 μmol/l (6.8 mg/dl)
- Willing to abstain from regular consumption of probiotic supplements or food products containing probiotic bacteria (including fermented food and...
You likely can't join if
- Recent (within last month) episode of gout
- Diagnosis of type 1 diabetes
- Diagnosed inflammatory bowel disease (IBD)
- Current diagnosis of psychiatric disease/s or syndromes
- Current diagnosis of neurodegenerative disease
- Current pregnancy or breastfeeding
See the full eligibility criteria
- Signed informed consent prior to any study-related procedures
- Age 18-80 years old
- BMI range 17.5-40 kg/m2
- Blood uric acid above 405 μmol/l (6.8 mg/dl)
- Willing to abstain from regular consumption of probiotic supplements or food products containing probiotic bacteria (including fermented food and beverages) during the study
- Willing to abstain from regular consumption of supplements and medications known to alter gastrointestinal function or inflammatory status during the study
- Recent (within last month) episode of gout
- Diagnosis of type 1 diabetes
- Diagnosed inflammatory bowel disease (IBD)
- Current diagnosis of psychiatric disease/s or syndromes
- Current diagnosis of neurodegenerative disease
- Current pregnancy or breastfeeding
- History of complicated gastrointestinal surgery
- (Partial) resection of the small intestine or colon
- Regular use of urate-lowering treatment (apart from allopurinol) in the month prior to inclusion
- Oral or intravenous administration of antibiotics and/or corticosteroids in the 4 months prior to inclusion
- Regular use of any non-steroidal anti-inflammatory drug (NSAID) during the last month prior to inclusion (apart from low-dose acetylsalicylic acid)
- Consumption of more than 9 standard glasses of alcohol-containing drinks per week and/or more than 4 standard glasses per occasion
- Regular use of probiotic or prebiotic supplementation in the month prior to inclusion
- Any condition or intake of medication which could substantially interfere with the outcome of the study, as decided by the principal investigator's discretion
The study team makes the final eligibility decision.
Where it's taking place
- Örebro, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Örebro, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.