BridgeMD
Tests treatment safety and results for Previous Endodontic Treatment Failure and...
Official title Efficacy of 810 nm Diode Laser Disinfection on Inflammatory Cytokines and Postoperative Pain After Endodontic Retreatment
ClinicalTrials.gov ID: NCT07141459
What this study is testing
What is Calcium Hydroxide Intracanal medication?
Calcium Hydroxide Intracanal medication is an investigational medicine, being studied as a potential treatment for previous endodontic treatment failure and radiographically confirmed periapical radiolucency.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The main cause of endodontic disorders is microbial infection. From the infected pulp tissue, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and lateral canals causing apical periodontitis.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 40, men only. Healthy volunteers may be eligible.
You may be able to join if
- Patients have single-rooted teeth with root canal form type I.
- Have previous endodontic therapy with failure.
- Have periapical radiolucency (PAI score of 3 or 4).
- Asymptomatic patients who had no pain or swelling had a negative response to palpation and percussion.
- Patients who provide written informed consent.
You likely can't join if
- Patients who had received antibiotic therapy within the past 3 months. Pregnancy and lactation.
- Systemic disease.
- Physical or mental disability.
- Non restorable teeth.
- Any signs of resorption, immature roots, fracture, sinus tract and dental anomaly
The study team makes the final eligibility decision.
Where it's taking place
- Cairo, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 20 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Cairo, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.