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New treatment option for Major Depression Moderate
Official title rTMS for Youth Inpatients With Depression
ClinicalTrials.gov ID: NCT07140575
What this study is testing
- What it's testing
- Youth aged 15-24 are likelier to have depression than all age groups in Canada. One-third of depressed youth do not respond to psychotherapy and/or antidepressant medications.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 14 to 19
You may be able to join if
- age 14-19 years
- primary diagnosis of major depressive disorder or of bipolar I or II disorder, current episode depressed with no psychotic or mixed features
- current episode of depression lasting at least 4 weeks
- failed ≥1 evidence-based psychotherapy or antidepressant
- have a GRID-HAMD-17 (17-item Hamilton Depression Rating Scale) score of ≥16 (moderate-severe range)
You likely can't join if
- lifetime diagnosis of a psychotic disorder, anorexia nervosa, bulimia nervosa diagnosis of a substance use disorder (except caffeine and tobacco)...
- obsessive compulsive disorder or personality disorder that is the main source and driver of distress
- active psychosis and/or mania
- history of epilepsy or any other neurologic condition that includes a history of seizures
- use of medications that lower the seizure threshold
- pregnancy or nursing
See the full eligibility criteria
- age 14-19 years
- primary diagnosis of major depressive disorder or of bipolar I or II disorder, current episode depressed with no psychotic or mixed features
- current episode of depression lasting at least 4 weeks
- failed ≥1 evidence-based psychotherapy or antidepressant
- have a GRID-HAMD-17 (17-item Hamilton Depression Rating Scale) score of ≥16 (moderate-severe range)
- currently an inpatient or suitable for an elective inpatient admission
- lifetime diagnosis of a psychotic disorder, anorexia nervosa, bulimia nervosa diagnosis of a substance use disorder (except caffeine and tobacco) within the past year
- obsessive compulsive disorder or personality disorder that is the main source and driver of distress
- active psychosis and/or mania
- history of epilepsy or any other neurologic condition that includes a history of seizures
- use of medications that lower the seizure threshold
- pregnancy or nursing
- history of severe headaches within the previous year
- improvement in depressive symptom severity between screening and baseline by 25% or more
- inability to adhere to the protocol
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 14 years to 19 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.