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New treatment option for Radiographic Axial Spondyloarthritis
Official title A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
ClinicalTrials.gov ID: NCT07133633
What this study is testing
What is Tulisokibart?
Tulisokibart is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for radiographic axial spondyloarthritis.
Also referred to as MK-7240, PRA023.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Researchers are looking for new ways to treat radiographic axial spondyloarthritis (r-axSpA). R-axSpA is a type of arthritis that causes pain, stiffness, and inflammation (swelling) in the spine and joints in the pelvis (hip bone).
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- The main include but are not limited to the following:
- Has a clinical diagnosis of axial spondyloarthritis (axSpA) and meets the Assessment of SpondyloArthritis international Society (ASAS) classification...
- Meets the radiographic criterion of the modified New York criteria for ankylosing spondylitis (AS) as determined by central reading at Screening
- Has active disease at Screening and Randomization
- Has a history of inadequate response (IR)/intolerance to nonsteroidal anti-inflammatory drugs (NSAIDs) and is biologic disease-modifying...
You likely can't join if
- The main exclusion criteria include but are not limited to the following:
- Has any arthritis with onset before age 17 years or current diagnosis of inflammatory joint disease other than radiographic axial spondyloarthritis...
- Has a history of cancer (except fully treated non-melanoma skin cancers or cervical carcinoma in situ after complete surgical removal) within the...
- Has any active infection
- Has known allergies, hypersensitivity, or intolerance to tulisokibart or its excipients
The study team makes the final eligibility decision.
Where it's taking place
- Chandler, Arizona, United States
- Flagstaff, Arizona, United States
- Gilbert, Arizona, United States
- Glendale, Arizona, United States
- Tucson, Arizona, United States
- Chula Vista, California, United States
- Fullerton, California, United States
- Huntington Beach, California, United States
- Thousand Oaks, California, United States
- Upland, California, United States
- Aventura, Florida, United States
- Brandon, Florida, United States
- Cooper City, Florida, United States
- Palmetto Bay, Florida, United States
- Chicago, Illinois, United States
- Willowbrook, Illinois, United States
- Baltimore, Maryland, United States
- Rockville, Maryland, United States
- Kansas City, Missouri, United States
- St Louis, Missouri, United States
+ 73 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chandler, Arizona, United States; Flagstaff, Arizona, United States; Gilbert, Arizona, United States; Glendale, Arizona, United States; Tucson, Arizona, United States; Chula Vista, California, United States and 87 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.