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New treatment option for High Altitude Effects
Official title HighCycle Study: Acetazolamide, High Altitude and Plasma Volume
ClinicalTrials.gov ID: NCT07118462
What this study is testing
What is Acetazolamide?
Acetazolamide is an investigational medicine, being studied as a potential treatment for high altitude effects.
Also referred to as Diamox®.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Each year, millions of people living at low altitude (\< 1,000 m) travel to high altitude (≥ 2,500 m) for work, tourism, or sports activities. These individuals are exposed to hypobaric hypoxia, which can trigger acute mountain sickness (AMS)-the most common form of altitude-related illness.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 44. Healthy volunteers may be eligible.
You may be able to join if
- Healthy, non-smoking men and women, age 18-44 years, without any disease and need of regular medication (including oral contraceptives).
- BMI \>18 kg/m2 and \<30 kg/m2.
- Born, raised and currently living at altitudes \<1000 m.
- Written informed consent.
- Premenopausal women with an eumenorrheic cycle.
You likely can't join if
- Other types of contraceptvies (contraceptives (hormonal intrauterine device, vaginal ring, subcutaneous injections or implants, among others).
- Pregnancy or nursing
- Anaemic (haemoglobin concentration \<10g/dl).
- Any altitude trip \<4 weks before the study.
- Allergy to acetazolamide and other sulfonamides.
The study team makes the final eligibility decision.
Where it's taking place
- Bishkek, Kyrgyzstan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 44 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bishkek, Kyrgyzstan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.