BridgeMD
New treatment option for THC
Official title THC Titration of High-Potency Cannabis Concentrates
ClinicalTrials.gov ID: NCT07105449
What this study is testing
What is Cannabis (30% THC Concentrate)?
Cannabis (30% THC Concentrate) is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for thc.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- High-potency cannabis use is associated with public health risks, such as cannabis use disorder, psychotic disorders, and impaired cognition. Legal markets in the US and Canada are geared towards the commercialization of high-tetrahydrocannabinol (THC) products, including concentrates as high as 90-95%.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 55. Healthy volunteers may be eligible.
You may be able to join if
- Age 19-55 years.
- Frequency of primary exposure to cannabis 1-4 occasions per week, through any route of administration, over the past three months; participants must...
- Refrain from cannabis for 48 hours and from alcohol for 12 hours before visits.
- Agree not to drive a car for 24 hours after each visit.
- Abstain from recreational drugs for at least 48 hours prior to each visit.
You likely can't join if
- Pregnant/breastfeeding (women of childbearing potential must have a negative pregnancy test and report use of appropriate contraception).
- Evidence of cardiac arrhythmias/failure, ischaemic heart disease.
- Recent open heart/open chest surgery or cataract surgery.
- Evidence from Structured Clinical Interview for DSM-5 [SCID-5-CT] or clinical evaluation of lifetime psychotic disorder/schizophrenia or bipolar...
- Evidence of neurological illness (e.g., stroke, epilepsy, traumatic brain injury).
- Renal or hepatic abnormalities (self-report and blood hematology/chemistry); and
See the full eligibility criteria
- Age 19-55 years.
- Frequency of primary exposure to cannabis 1-4 occasions per week, through any route of administration, over the past three months; participants must report experience with vaping high-potency liquid concentrates with...
- Refrain from cannabis for 48 hours and from alcohol for 12 hours before visits.
- Agree not to drive a car for 24 hours after each visit.
- Abstain from recreational drugs for at least 48 hours prior to each visit.
- Abstain from any drugs not medically required.
- Well-controlled blood pressure for participants with hypertension.
- Pregnant/breastfeeding (women of childbearing potential must have a negative pregnancy test and report use of appropriate contraception).
- Evidence of cardiac arrhythmias/failure, ischaemic heart disease.
- Recent open heart/open chest surgery or cataract surgery.
- Evidence from Structured Clinical Interview for DSM-5 [SCID-5-CT] or clinical evaluation of lifetime psychotic disorder/schizophrenia or bipolar disorder; family history of a first-degree relative with a diagnosis of...
- Evidence of neurological illness (e.g., stroke, epilepsy, traumatic brain injury).
- Renal or hepatic abnormalities (self-report and blood hematology/chemistry); and
- Respiratory diseases, including asthma and physician-diagnosed lung disease.
- Taking prescribed medications that contain either THC or cannabidiol (CBD).
- Participation in another clinical or non-therapeutic study in the last three months.
- Bleeding disorders.
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.