BridgeMD
New treatment option for Post Operative Pain
Official title Preoperative Acetazolamide
ClinicalTrials.gov ID: NCT07101250
What this study is testing
What is Acetazolamide 500 MG Extended Release Oral Capsule?
Acetazolamide 500 MG Extended Release Oral Capsule is an investigational medicine, being studied as a potential treatment for post operative pain.
Also referred to as Diamox.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 65, women only
You may be able to join if
- Women
- Ages 21-65
- undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without bilateral salpingoophorectomy
- undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without cystoscopy
You likely can't join if
- Allergy to acetazolamide or sulfonamides
- Known electrolyte disturbances
- Pregnancy
- Kidney failure or creatinine \>1.5
- Diuretic or lithium use
- Chronic obstructive pulmonary disease (COPD) or other lung disease
See the full eligibility criteria
- Women
- Ages 21-65
- undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without bilateral salpingoophorectomy
- undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without cystoscopy
- Allergy to acetazolamide or sulfonamides
- Known electrolyte disturbances
- Pregnancy
- Kidney failure or creatinine \>1.5
- Diuretic or lithium use
- Chronic obstructive pulmonary disease (COPD) or other lung disease
- Central nervous system disorders
- Liver disease
- Glaucoma
- Preoperative or chronic opioid use
- Diagnosis of fibromyalgia
- Preoperative shoulder pain
- Conversion to laparotomy
- Intraoperative bladder or bowel injury
- Inability to understand or utilize visual analog scale
- Undergoing concurrent reconstructive procedures
The study team makes the final eligibility decision.
Where it's taking place
- Greenville, South Carolina, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 21 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Greenville, South Carolina, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.