BridgeMD
New treatment option for Community-Acquired Pneumonia (CAP)
Official title PromotIng Optimal Treatment for Community-acquired PNeumonia in EmErgency Rooms
ClinicalTrials.gov ID: NCT07099976
What this study is testing
- What it's testing
- In North America, up to 5% of preschoolers develop community-acquired pneumonia (CAP) every year. Pneumonia is the second-leading reason for paediatric hospitalization in both Canada and the US; approximately 20% of children hospitalized with CAP may need intensive care, which can result in significant morbidity.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 6 to 18
You may be able to join if
- Children aged 6 month to 18 years presenting to the Emergency Department who are diagnosed with CAP and are well enough to be discharged home (i.e...
- Tachypnoea measured at triage (\>60 bpm for age \ 50 for 1-2 years of age, \>40bpm for 2-4 years of age, and \>30bpm for \>4 years of age)
- Cough on exam or by history
- Increased work of breathing on exam
- Auscultatory finding (focal crackles, bronchial breathing, etc.) consistent with CAP
You likely can't join if
- Children will be excluded if they have any of the following
- Cystic Fibrosis
- Anatomic Lung Disease
- Bronchiectasis
- Chronic Lung Disease requiring home oxygen or home ventilation
- Congenital heart Disease (requiring specific medical treatment or with exercise restrictions),
See the full eligibility criteria
- Children aged 6 month to 18 years presenting to the Emergency Department who are diagnosed with CAP and are well enough to be discharged home (i.e. 'non-severe' CAP) will be eligible. They must have a fever (on exam or...
- Tachypnoea measured at triage (\>60 bpm for age \ 50 for 1-2 years of age, \>40bpm for 2-4 years of age, and \>30bpm for \>4 years of age)
- Cough on exam or by history
- Increased work of breathing on exam
- Auscultatory finding (focal crackles, bronchial breathing, etc.) consistent with CAP
- Children will be excluded if they have any of the following
- Cystic Fibrosis
- Anatomic Lung Disease
- Bronchiectasis
- Chronic Lung Disease requiring home oxygen or home ventilation
- Congenital heart Disease (requiring specific medical treatment or with exercise restrictions),
- History of repeated aspiration/velopharyngeal incompetence
- Malignancy
- Immunodeficiency (primary, acquired or iatrogenic)
- Pneumonia previously (clinically) diagnosed within the past month (that was presumed to have resolved prior to the episode prompting the current visit to the ED)
- Lung abscess within the past 6 months
- Children who present with ongoing fever after 4 days of amoxicillin, cefprozil, cefuroxime, levofloxacin, moxifloxacin or doxycycline are not eligible; as this duration of therapy with these drugs would normally be...
- Children will not be eligible to participate more than once
The study team makes the final eligibility decision.
Where it's taking place
- Calgary, Alberta, Canada
- Edmonton, Alberta, Canada
- Vancouver, British Columbia, Canada
- Hamilton, Ontario, Canada
- Ottawa, Ontario, Canada
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 6 months to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Calgary, Alberta, Canada; Edmonton, Alberta, Canada; Vancouver, British Columbia, Canada; Hamilton, Ontario, Canada; Ottawa, Ontario, Canada; Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.