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New treatment option for Healthy
Official title A Study of LY4088044 in Healthy Participants
ClinicalTrials.gov ID: NCT07090785
What this study is testing
What is LY4088044?
LY4088044 is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for healthy.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to evaluate how well LY4088044 is tolerated and what side effects may occur in healthy participants. The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm).
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Are overtly healthy as determined by medical evaluation including medical history, physical examination, laboratory tests, vital signs, and cardiac...
- Have a body mass index (BMI) within the range 18.5 to 30 kilogram per square meter (kg/m²)
You likely can't join if
- Are individuals assigned female at birth (AFAB) who are pregnant and/or lactating
- Regularly use known drugs of abuse or show positive findings on urinary drug screening that are not consistent with their medication history
- Participants with hemoglobin outside of the local laboratory normal range for age and gender, or evidence of iron deficiency, or hemoglobinopathy
- Participants with estimated glomerular filtration rate (GFR) less than 90 milliliter per minute per 1.73 square meter (mL/min/1.73 m²)
- Have a 12-lead electrocardiogram (ECG) abnormality
- Smoke more than 10 cigarettes per day or the equivalent including electronic cigarettes AND are unable to abide by investigative site smoking...
See the full eligibility criteria
- Are overtly healthy as determined by medical evaluation including medical history, physical examination, laboratory tests, vital signs, and cardiac monitoring
- Have a body mass index (BMI) within the range 18.5 to 30 kilogram per square meter (kg/m²)
- Are individuals assigned female at birth (AFAB) who are pregnant and/or lactating
- Regularly use known drugs of abuse or show positive findings on urinary drug screening that are not consistent with their medication history
- Participants with hemoglobin outside of the local laboratory normal range for age and gender, or evidence of iron deficiency, or hemoglobinopathy
- Participants with estimated glomerular filtration rate (GFR) less than 90 milliliter per minute per 1.73 square meter (mL/min/1.73 m²)
- Have a 12-lead electrocardiogram (ECG) abnormality
- Smoke more than 10 cigarettes per day or the equivalent including electronic cigarettes AND are unable to abide by investigative site smoking restrictions
- Have an average weekly alcohol intake that exceeds 21 units per week (males less than or equal to 65 years old) and 14 units per week (females and males over 65-year-old, if applicable) and are unwilling to abide by the...
The study team makes the final eligibility decision.
Where it's taking place
- Los Alamitos, California, United States
- Lenexa, Kansas, United States
- San Antonio, Texas, United States
- Salt Lake City, Utah, United States
- Christchurch, New Zealand
- Singapore, Singapore
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Los Alamitos, California, United States; Lenexa, Kansas, United States; San Antonio, Texas, United States; Salt Lake City, Utah, United States; Christchurch, New Zealand; Singapore, Singapore. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.