BridgeMD
New treatment option for Knee Arthroplasty, Total
Official title The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
ClinicalTrials.gov ID: NCT07089251
What this study is testing
What is low-dose epinephrine and tranexamic acid?
low-dose epinephrine and tranexamic acid is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for knee arthroplasty, total.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing knee joint arthroplasty. Also aim to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative thromboembolic complications, and hospitalization duration
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Patients undergoing knee joint arthroplasty.
- Saudi and Non-Saudi Patient.
- Patients who have Complete medical record.
You likely can't join if
- End stage renal disease
- Liver cirrhosis
- Coagulopathy
- Pre-operative Hgb \<10 5.
- History of cerebrovascular accident or myocardial infarction in past 12 months.
- History of Heart failure.
See the full eligibility criteria
- Patients undergoing knee joint arthroplasty.
- Saudi and Non-Saudi Patient.
- Patients who have Complete medical record.
- End stage renal disease
- Liver cirrhosis
- Coagulopathy
- Pre-operative Hgb \<10 5.
- History of cerebrovascular accident or myocardial infarction in past 12 months.
- History of Heart failure.
- History of arrhythmia.
- History of pheochromocytoma, thyrotoxicosis and glaucoma.
- Pregnancy or breast feeding
- History of Deep venous thrombosis or pulmonary embolism
- Allergy to epinephrine or tranexamic acid
The study team makes the final eligibility decision.
Where it's taking place
- Riyadh, Riyadh Region, Saudi Arabia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Riyadh, Riyadh Region, Saudi Arabia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.