BridgeMD
New treatment option for Epilepsy
Official title Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Epileptic Patients With Hypovitaminosis D
ClinicalTrials.gov ID: NCT07085598
What this study is testing
- What it's testing
- The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male epileptic patients with hypovitaminosis D that weather vitamin D improves heart rate variability or not. The main questions it aims to answer are: 1.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 40, men only
You may be able to join if
- Diagnosed male patients with Epilepsy by neurologist from the OPD of Department of Neurology by taking proper history of at least two unprovoked (or...
- Having hypovitaminosis D (serum vitamin D3 level \<30 ng/ml)
- Age: 20-40 years.
- Sex: Male
- BMI : 18.5-24.9 kg/m2
You likely can't join if
- Epileptic patients taking Sodium valproate, oxcarbazepine, Topiramate, Lamotrigine, Levetiracetam.
- Patient having absence seizure
- Alcoholic
- Smoker
- Patients taking following drugs will be excluded-
- Anti-diabetic drugs
See the full eligibility criteria
- Diagnosed male patients with Epilepsy by neurologist from the OPD of Department of Neurology by taking proper history of at least two unprovoked (or reflex) seizures occuring \> 24 hours apart, from patients and eye...
- Having hypovitaminosis D (serum vitamin D3 level \<30 ng/ml)
- Age: 20-40 years.
- Sex: Male
- BMI : 18.5-24.9 kg/m2
- Taking antiepileptic drug for 6 months to 2 years ( Enzyme inducer AEDs, e.g. Carbamazepine, Phenytoin, Phenobarbital)
- Without medication that affect central nervous system other than antiepileptic drugs (AEDs).
- Epileptic patients taking Sodium valproate, oxcarbazepine, Topiramate, Lamotrigine, Levetiracetam.
- Patient having absence seizure
- Alcoholic
- Smoker
- Patients taking following drugs will be excluded-
- Anti-diabetic drugs
- Antioxidant vitamin supplements
- Antihypertensive drug
- Anti-arrhythmic drug
- Lipid lowering medications
- Sedatives
- Patients having known hypersensitivity to vitamin D3
- All patients with the history of or currently suffering from following diseases \& condition will be excluded-
- Cardiovascular disorders (Myocardial infarction, coronary heart disease, cardiac arrhythmia, CCF)
- Other neurological disorders (Migraine, stroke)
- Respiratory disorders (Bronchial asthma, COPD)
- Renal insufficiency (S. Creatinine \> 1.5 mg/dl, Acute or chronic kidney disease)
- Endocrine disease (Diabetes mellitus, Thyroid disorders- hypothyroidism, hyperthyroidism)
- Arthritis (rheumatoid arthritis)
- Liver diseases
- Neoplastic disease
- Psychiatric disorder (schizophrenia, bipolar disorder)
- Current use of iron, zinc, calcium, magnesium and multivitamin supplementation
- Already performing yoga or breathing exercise
- Patients with hypercalcemia
The study team makes the final eligibility decision.
Where it's taking place
- Dhaka, Shahbag, Bangladesh
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 20 years to 40 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dhaka, Shahbag, Bangladesh. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.