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Compares treatment options for Chronic Apical Periodontitis
Official title Sonic vs Passive Ultrasonic Irrigation for Chronic Apical Periodontitis
ClinicalTrials.gov ID: NCT07069881
What this study is testing
- What it's testing
- This randomized, controlled, double-blinded clinical trial aims to directly compare the efficacy of Sonically Activated Irrigation (SAI) versus Passive Ultrasonic Irrigation (PUI) in the root canal treatment of teeth with chronic apical periodontitis, analyze potential influencing factors, and thereby identify a highly effective and safe root canal irrigation protocol. The ultimate goal is to provide an evidence-based rationale for optimizing irrigation technique selection and overall treatment strategies for chronic apical periodontitis.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 59
You may be able to join if
- Agree to participate in this study and provide informed consent;
- Age 18-59 years at the time of enrolment;
- At least one permanent tooth diagnosed with chronic periapical periodontitis at root development stage of Nolla10th;
- Able to follow up on schedule.
You likely can't join if
- Allergies to any medications or materials necessary to complete the procedures;
- Non-restorable teeth, teeth with severe defects, or teeth that need to be extracted due to orthodontic treatment;
- Teeth with root canal treatment or vital pulp therapy;
- Teeth with canal calcification or root canal instrument separation;
- Teeth with root fracture or vertical root fracture;
- Tooth with internal or external root resorption;
See the full eligibility criteria
- Agree to participate in this study and provide informed consent;
- Age 18-59 years at the time of enrolment;
- At least one permanent tooth diagnosed with chronic periapical periodontitis at root development stage of Nolla10th;
- Able to follow up on schedule.
- Allergies to any medications or materials necessary to complete the procedures;
- Non-restorable teeth, teeth with severe defects, or teeth that need to be extracted due to orthodontic treatment;
- Teeth with root canal treatment or vital pulp therapy;
- Teeth with canal calcification or root canal instrument separation;
- Teeth with root fracture or vertical root fracture;
- Tooth with internal or external root resorption;
- Patients with periodontitis;
- Patients with orthodontic treatment;
- Presence of dental phobia;
- Women who are pregnant;
- Patients who have taken medications that affect central nervous system, such as tricyclic antidepressant;
- Patients who have taken medications that affect immune response, such as glucocorticoid or cyclosporin;
- Patients after radiotherapy of tumor head and neck;
- Patients who have taken medications that affect curative effect, such as bisphosphonates;
- Patients with serious systemic diseases that can affect curative effect;
- Participation in other clinical studies within the past several weeks;
- Patients who are deemed unsuitable to participate in the study by investigators.
The study team makes the final eligibility decision.
Where it's taking place
- Guangzhou, Guangdong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 59 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guangzhou, Guangdong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.