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New treatment option for Female Infertility
Official title Adipose Stem Cell Mitochondria Supplementation to Oocytes (ASCENT)
ClinicalTrials.gov ID: NCT07066267
What this study is testing
- What it's testing
- The purpose of this study is to investigate the potential of autologous adipose stem cell (ASC) mitochondrial transfer (ASCENT) to oocytes along with intracytoplasmic sperm injection (ICSI)as a means of enhancing embryo development and improving the success rate of in patients with a history of multiple IVF failures. Embryo quality plays a crucial role in determining the success of assisted reproductive technologies and directly contributes to repeated pregnancy failures.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 29 to 39, women only
You may be able to join if
- Having at least three previous failed IVF trial
- Specifically consented for to collect biopsies for Preimplantation generic testing for aneuploidy (PGTA) analysis
- Specifically consented for to have single blastocyst transfer (recommended)
- No major uterine or ovarian abnormalities
- Specifically consented for to have all embryos frozen
You likely can't join if
- Ovarian endometriosis with Chocolate cysts (American Fertility Society (AFS)) classification type 3 and 4
- Any medical contraindication oocyte retrieval or subsequent procedures Ovarian hyperstimulation syndrome Bleeding disorders Sex hormone allergies...
- Severe sperm abnormalities
- \<5 million/mL motile sperm
- Uterine structural anomalies
- Polycystic ovaries
See the full eligibility criteria
- Having at least three previous failed IVF trial
- Specifically consented for to collect biopsies for Preimplantation generic testing for aneuploidy (PGTA) analysis
- Specifically consented for to have single blastocyst transfer (recommended)
- No major uterine or ovarian abnormalities
- Specifically consented for to have all embryos frozen
- Specifically consented for to collect adipose tissues from subcutaneous liposuction
- BMI level level \<26kg/m2
- Ovarian endometriosis with Chocolate cysts (American Fertility Society (AFS)) classification type 3 and 4
- Any medical contraindication oocyte retrieval or subsequent procedures Ovarian hyperstimulation syndrome Bleeding disorders Sex hormone allergies Severe emotional defect on injections
- Severe sperm abnormalities
- \<5 million/mL motile sperm
- Uterine structural anomalies
- Polycystic ovaries
- Premature ovarian failure
The study team makes the final eligibility decision.
Where it's taking place
- Colombo, Sri Lanka
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 29 years to 39 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Colombo, Sri Lanka. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.