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New treatment option for Satiation, Satiety
Official title The Chocolate Almond Study - Relating Chewing to Satiation and Postprandial Response
ClinicalTrials.gov ID: NCT07065461
What this study is testing
- What it's testing
- The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are: Does the presence or preparation of almonds (whole versus chopped) influence satiation, i.e., the amount consumed at an ad libitum meal?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, women only. Healthy volunteers may be eligible.
You may be able to join if
- BMI between 18.5-27.9 kg/m\^2 or waist circumference less than 88 cm
- No known food allergies or sensitivities
- Non-restrained eaters based on the Three Factor Eating Questionnaire
- No history of gastrointestinal diseases that may interfere with eating behaviour or digestion
- Not on medications that affect appetite, digestion, blood sugar regulation, saliva production, or chewing
You likely can't join if
- Diabetes or other metabolic disorders affecting glycemia and overall cardiometabolic health
- Any food allergies, intolerance, or sensitivities
- Any life-threatening allergy
- Pregnant or breastfeeding
- Participation in another clinical trial
- Alcohol consumption more than 14 drinks per week
See the full eligibility criteria
- BMI between 18.5-27.9 kg/m\^2 or waist circumference less than 88 cm
- No known food allergies or sensitivities
- Non-restrained eaters based on the Three Factor Eating Questionnaire
- No history of gastrointestinal diseases that may interfere with eating behaviour or digestion
- Not on medications that affect appetite, digestion, blood sugar regulation, saliva production, or chewing
- Stable medication use
- Non-smokers
- Not gained or lost significant weight during the past 3 months
- Regular monthly menstrual cycles
- Not pregnant, lactating, or post-menopausal
- Diabetes or other metabolic disorders affecting glycemia and overall cardiometabolic health
- Any food allergies, intolerance, or sensitivities
- Any life-threatening allergy
- Pregnant or breastfeeding
- Participation in another clinical trial
- Alcohol consumption more than 14 drinks per week
- Smokers or those with a smoking history or more than 10 years
- Regular use of recreational drugs (e.g., marijuana, ecstasy, magic mushrooms)
- Restrained eater as defined by \> 15 on the Three-Factor Eating Questionnaire
- Unusual sleep patterns
- Irregular breakfast consumption
- Recent weight changes or intended weight loss or gain or having lost or gained \>10% of body weight within the last 6 months
- Using medications known to affect appetite, digestion, blood sugar regulation, lipids, or chewing (excluding oral contraceptives)
- Experiences dry mouth, in general or due to medication side effects
- Diagnosed with Sjogren's Syndrome (autoimmune condition linked to severe dry mouth)
- Inability to adhere to study protocols
- Not comfortable providing finger prick blood samples
- Avoids consuming almonds or chocolate
- Has temporomandibular joint disorder (TMJ)
- Has or history or oral cancer
- Recent dental or jaw surgery
- Avoids eating hard foods for concerns of dental fractures or for general oral health
- Individuals with dentures, braces, Invisalign, or other dental implants that cause difficulty chewing
The study team makes the final eligibility decision.
Where it's taking place
- Guelph, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guelph, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.