BridgeMD
Compares treatment options for Sevoflurane
Official title Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy
ClinicalTrials.gov ID: NCT07062367
What this study is testing
What is Propofol?
Propofol is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for sevoflurane.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study will be conducted to evaluate the effects of different anesthetic modalities [sevoflurane with or without intraoperative lidocaine infusion and Propofol total intravenous anesthesia (TIVA)] on intracranial pressure (ICP) and cerebral oxygenation assessed by non-invasive methods during laparoscopic hysterectomy (LH).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65, women only
You may be able to join if
- Age from 18 to 65 years.
- American Society of Anesthesiologists (ASA) physical status I and Ⅱ.
- Body mass index (BMI) ≤35.
- Females scheduled for laparoscopic hysterectomy.
You likely can't join if
- Patients' refusal to participate in the study.
- Hypersensitivity and allergy to drugs of the study.
- Contraindication for optic nerve sheath diameter assessment. E.g., patient with pre-existing ophthalmic diseases, a history of ophthalmic surgery
- Any central nervous system or cardiovascular disease, severe hepatic or renal impairment
- Intraoperative circumstances, such as inability to perform optic nerve sheath diameter or conversion to open surgery
- If peak inspiratory pressure (PIP) exceeds 35.
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, El-Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, El-Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.