BridgeMD
New treatment option for Hematopoietic Stem Cell Transplantation (HSCT)
Official title Effects of Different Inspiratory Muscle Training Protocols in Hematopoietic Stem Cell Transplant Recipients
ClinicalTrials.gov ID: NCT07061444
What this study is testing
- What it's testing
- Introduction: After haematopoietic stem cell transplantation (HSCT), patients often experience complications such as respiratory difficulties, fatigue and decreased quality of life. The aim of the study was to compare the effectiveness of different inspiratory muscle training (IMT) protocols on respiratory muscle strength and endurance, dyspnoea, maximal exercise capacity, diaphragmatic function, respiratory function parameters, peripheral muscle strength, fatigue, quality of life, oxidative stress parameters, muscle biomarkers and inflammatory biomarkers in HSCT recipients during the transplantation process.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Planned haematopoietic stem cell transplantation in the adult bone marrow transplant unit
- Between the ages of 18-65
- Under standard medical treatment, including immunosuppressives, antibiotics and other medications
- Ability to walk, co-operate and be clinically stable
- No history of orthopaedic, neurological, cardiac disorders
You likely can't join if
- Cognitive disorders
- Have orthopaedic or neurological diseases that may affect the assessment of physical fitness tests
- Having comorbidities such as asthma, COPD
- Conditions in which exercise training is contraindicated, such as acute bleeding, haemoglobin value \ 38◦C), severe pain, confusion, dizziness...
- Patients with pneumonia or any acute infection -≥ 3 consecutive sessions of interruption of the exercise group people' attendance to the training...
- Loss of willingness to participate in the research during the research process
See the full eligibility criteria
- Planned haematopoietic stem cell transplantation in the adult bone marrow transplant unit
- Between the ages of 18-65
- Under standard medical treatment, including immunosuppressives, antibiotics and other medications
- Ability to walk, co-operate and be clinically stable
- No history of orthopaedic, neurological, cardiac disorders
- Cognitive disorders
- Have orthopaedic or neurological diseases that may affect the assessment of physical fitness tests
- Having comorbidities such as asthma, COPD
- Conditions in which exercise training is contraindicated, such as acute bleeding, haemoglobin value \ 38◦C), severe pain, confusion, dizziness, nausea and vomiting
- Patients with pneumonia or any acute infection -≥ 3 consecutive sessions of interruption of the exercise group people' attendance to the training protocol
- Loss of willingness to participate in the research during the research process
- Development of clinical haemodynamic instability in patients
The study team makes the final eligibility decision.
Where it's taking place
- Istanbul, Zeytinburnu, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Istanbul, Zeytinburnu, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.