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New treatment option for Oxidative Stress
Official title Effect of Different Root Canal Sealers on Oxidative Stress Markers
ClinicalTrials.gov ID: NCT07059481
What this study is testing
- What it's testing
- The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session. The main questions it aims to answer are: Is there a change in oxidative stress markers measured from saliva after root canal treatment?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Systemically healthy, ASA1 patients,
- Phase 1 periodontal treatment was performed,
- Diagnosed with chronic apical periodontitis in a single tooth with 2 or more roots in the mouth,
- The lesion measured \<2 cm on radiographic evaluation,
- The vitality of the tooth was checked by EPT (Ai-Pex, Woodpecker, China) and Cold test (Cerkamed, Poland) and confirmed to be devitalised,
You likely can't join if
- Patients who have used antibiotics in the last three months and analgesics in the last two weeks
- Patients who smoke and/or abuse alcohol
- Patients younger than 18 years or older than 45 years,
- Patients with controlled or uncontrolled systemic disease and life-threatening conditions (ASA 2,3,4,5,6)
- Pregnant or lactating women,
- Patients with poor oral hygiene,
See the full eligibility criteria
- Systemically healthy, ASA1 patients,
- Phase 1 periodontal treatment was performed,
- Diagnosed with chronic apical periodontitis in a single tooth with 2 or more roots in the mouth,
- The lesion measured \<2 cm on radiographic evaluation,
- The vitality of the tooth was checked by EPT (Ai-Pex, Woodpecker, China) and Cold test (Cerkamed, Poland) and confirmed to be devitalised,
- Socioculturally able to participate in the treatment,
- Individuals who did not smoke or drink alcohol
- Patients who have used antibiotics in the last three months and analgesics in the last two weeks
- Patients who smoke and/or abuse alcohol
- Patients younger than 18 years or older than 45 years,
- Patients with controlled or uncontrolled systemic disease and life-threatening conditions (ASA 2,3,4,5,6)
- Pregnant or lactating women,
- Patients with poor oral hygiene,
- Patients who had head and neck radiotherapy,
- With obesity,
- Active periodontal disease,
- Periodontal pocket depth over 3mm,
- There is enough loss of material in the relevant tooth to prevent adequate isolation or to require post placement,
- Clinical examination of the relevant tooth showing symptoms in percussion-palpation,
- Radiographically, the lesion is seen in relation to anatomical formations such as the mandibular canal and maxillary sinus,
- Patients who required prophylactic antibiotic use before invasive dental procedures were excluded from the study.
- Patients who did not attend the follow-up appointment and patients who experienced complications during expansion (instrument seperation, perforation, etc.) were excluded from the study.
The study team makes the final eligibility decision.
Where it's taking place
- Ordu, Ordu- Altınordu, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ordu, Ordu- Altınordu, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.