BridgeMD
New treatment option for Left Bundle Branch Block
Official title UHF ECG in LBBB and Response to CRT Prediction
ClinicalTrials.gov ID: NCT07057544
What this study is testing
- What it's testing
- The main objective of the project is to demonstrate that in patients with heart failure and QRS complex of nonRBBB morphology lasting over 130 ms, UHF-ECG can differentiate patients with trueLBBB from IVCD better than existing approaches based on the assessment of QRS complex morphology and duration from 12-lead ECG. Another goal of the proposed study is to demonstrate that trueLBBB patients will benefit more from CRT using left bundle branch pacing than from CRT using biventricular pacing.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- HF due to ischemic or non-ischemic cardiomyopathy
- known coronary angiography
- NYHA II-IV
- LVEF ≤40%
- non-RBBB QRSd lasting \>130 ms (by automated measurement)
You likely can't join if
- Age ˂18 years
- heart failure from reversible causes
- Moderate to severe aortic stenosis
- pregnancy
- active myocarditis
- hypertrophic cardiomyopathy
See the full eligibility criteria
- HF due to ischemic or non-ischemic cardiomyopathy
- known coronary angiography
- NYHA II-IV
- LVEF ≤40%
- non-RBBB QRSd lasting \>130 ms (by automated measurement)
- proximal LBBB proved by an invasive EP study or non-invasive dyssynchrony assessment in case such a method is confirmed to be non-inferior to an invasive EP study during the project
- Age ˂18 years
- heart failure from reversible causes
- Moderate to severe aortic stenosis
- pregnancy
- active myocarditis
- hypertrophic cardiomyopathy
- cardiac valve surgery in the last three months
- myocardial infarction, PCI, or CABG in the last three months
- severe valvular disease requiring intervention
- severe atherosclerotic disease of the aorta and/or femoral arteries
- life expectancy ˂1 year
- known medical condition or contraindication causing potential complications for EP study
The study team makes the final eligibility decision.
Where it's taking place
- Prague, Česká Republika, Czechia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Prague, Česká Republika, Czechia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.