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New treatment option for Post-stroke Upper Limb Hemiparesis
Official title Repetitive Transcranial Magnetic Stimulation Combined With Bimanual Therapy for Upper Limb Stroke Rehabilitation
ClinicalTrials.gov ID: NCT07054424
What this study is testing
- What it's testing
- The goal of this clinical trial is to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with machine-assisted bimanual therapy (BT) can improve upper limb function in stroke patients. The participants will be individuals aged 40-80 years who have experienced a first-time ischemic or hemorrhagic stroke.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 80
You may be able to join if
- Age 40-80 years;
- First-onset stroke patients;
- Patients diagnosed with cerebral infarction or hemorrhage through CT or MRI;
- Signed informed consent form by the patient and their family;
- Stable physiological parameters;
You likely can't join if
- A history of epilepsy or family history of epilepsy;
- Presence of suicidal tendencies;
- Currently using medications that lower the seizure threshold;
- Pregnant or planning to become pregnant;
- Co-existing neurological diseases (such as multiple sclerosis, other neurodegenerative diseases, meningitis, brain abscess, or meningioma);
- people with uncontrollable migraines caused by elevated intracranial pressure;
See the full eligibility criteria
- Age 40-80 years;
- First-onset stroke patients;
- Patients diagnosed with cerebral infarction or hemorrhage through CT or MRI;
- Signed informed consent form by the patient and their family;
- Stable physiological parameters;
- Stroke occurred within the last 12 months;
- Patients with unilateral hand function impairment caused by the stroke;
- Upper limb muscle tone (Modified Ashworth Scale, MAS) less than 3 points;
- Able to follow two-step commands.
- A history of epilepsy or family history of epilepsy;
- Presence of suicidal tendencies;
- Currently using medications that lower the seizure threshold;
- Pregnant or planning to become pregnant;
- Co-existing neurological diseases (such as multiple sclerosis, other neurodegenerative diseases, meningitis, brain abscess, or meningioma);
- people with uncontrollable migraines caused by elevated intracranial pressure;
- people taking antidepressants who cannot discontinue the medication;
- people with sleep disorders during rTMS treatment;
- people with cerebellar stroke or brainstem stroke;
- Cerebral ischemic disorders resulting from traumatic brain injury;
- Transient ischemic attacks (TIAs);
- History of bleeding tendency and other conditions affecting upper limb function, such as myasthenia gravis, systemic immune neuropathy, severe epilepsy, endocrine system disorders, wearers of external or internal...
- Co-existing severe heart, liver, kidney dysfunction, or other serious physical illnesses;
- people with impaired consciousness who cannot cooperate with examinations or treatments, such as those with mental disorders, or those with intellectual or cognitive impairments, severe dementia;
- Presence of implanted electronic devices in the body;
- Co-existing severe liver, kidney, or hematological disorders;
- Special vulnerable populations;
- Skin disease (e.g., pressure ulcers, trauma, cellulitis, etc.).
The study team makes the final eligibility decision.
Where it's taking place
- Taoyuan, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taoyuan, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.