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New treatment option for Acne Vulgaris
Official title Assessment of Serum Catestatin Level in Acne Vulgaris Patients
ClinicalTrials.gov ID: NCT07054398
What this study is testing
What is Isotretinoin?
Isotretinoin is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for acne vulgaris.
Also referred to as Catestatin.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Acne vulgaris is a persistent inflammatory condition of the pilosebaceous unit, affecting 85% of people between the ages of 12 and 24, it is regarded as one of the most common diseases in teenagers and young adults. Catestatin, a peptide derived from chromogranin A (CgA), was first discovered in 1997 as an acute nicotinic-cholinergic antagonist.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40. Healthy volunteers may be eligible.
You may be able to join if
- Healthy persons of both sexes with moderate and severe acne.
You likely can't join if
- Pregnant and lactating women.
- Immunocompromised patients.
- Severe anemia.
- History of chronic liver disease.
- Hyperlipidemia
- Non-inflammatory acne conditions.
See the full eligibility criteria
- Healthy persons of both sexes with moderate and severe acne.
- Pregnant and lactating women.
- Immunocompromised patients.
- Severe anemia.
- History of chronic liver disease.
- Hyperlipidemia
- Non-inflammatory acne conditions.
- History of neurologic disorders.
- History of neoplastic disorders.
- History of cardiac disease.
- History of systemic acne treatment for at least 4 weeks prior to inclusion and no topical treatments for at least 2 weeks.
- Cases with known hypersensitivity reaction to isotretinoin.
The study team makes the final eligibility decision.
Where it's taking place
- Aswān, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Aswān, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.