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New treatment option for Thyroid Nodule (Benign)
Official title Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules
ClinicalTrials.gov ID: NCT07046546
What this study is testing
- What it's testing
- Large non-cancerous thyroid nodules (lumps in the thyroid gland) can cause pressure or discomfort in the neck or cosmetic issues. The standard treatment options include radiofrequency ablation, radioactive iodine, and surgery.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- The participant may enter the study if ALL of the following apply:
- Adults over 18 years of age willing and able to give informed consent.
- Symptomatic or cosmetically distressing benign nodular thyroid disease with or without intrathoracic extension and with or without hyperthyroidism...
- Single nodular goitre causing local mass effect warranting treatment or multi-nodular goitre
- TIRADS score 1, 2 and 3 nodules (benign or mildly suspicious) as assessed by ultrasound.
You likely can't join if
- The participant may enter the study if ALL of the following apply:
- Adults over 18 years of age willing and able to give informed consent.
- Symptomatic or cosmetically distressing benign nodular thyroid disease with or without intrathoracic extension and with or without hyperthyroidism...
- Single nodular goitre causing local mass effect warranting treatment or multi-nodular goitre
- TIRADS score 1, 2 and 3 nodules (benign or mildly suspicious) as assessed by ultrasound.
- FNA confirmed benign disease (x2 FNA Thy2 (benign) result required for TR3 nodules, 1x FNA if nodule classified TR2 or less). FNA performed on most...
See the full eligibility criteria
- The participant may enter the study if ALL of the following apply:
- Adults over 18 years of age willing and able to give informed consent.
- Symptomatic or cosmetically distressing benign nodular thyroid disease with or without intrathoracic extension and with or without hyperthyroidism. Or auto-immune hyperthyroidism (Graves disease).
- Single nodular goitre causing local mass effect warranting treatment or multi-nodular goitre
- TIRADS score 1, 2 and 3 nodules (benign or mildly suspicious) as assessed by ultrasound.
- FNA confirmed benign disease (x2 FNA Thy2 (benign) result required for TR3 nodules, 1x FNA if nodule classified TR2 or less). FNA performed on most high grade nodule or if equal grade then largest nodule.
- No enlarged / suspicious neck lymphadenopathy on ultrasound.
- Patient willing to undergo thyroid nodule embolization in preference to other viable treatment options after discussion with Consultant ENT surgeon and / or Consultant treatment Radiologist. TAE can also be performed as...
- Patient able to lay on the angiography table flat with one or two pillows, and can lay comfortably with 30 degrees or less of head elevation for a minimum of two hours.
- The participant may enter the study if ALL of the following apply:
- Adults over 18 years of age willing and able to give informed consent.
- Symptomatic or cosmetically distressing benign nodular thyroid disease with or without intrathoracic extension and with or without hyperthyroidism. Or auto-immune hyperthyroidism (Graves disease).
- Single nodular goitre causing local mass effect warranting treatment or multi-nodular goitre
- TIRADS score 1, 2 and 3 nodules (benign or mildly suspicious) as assessed by ultrasound.
- FNA confirmed benign disease (x2 FNA Thy2 (benign) result required for TR3 nodules, 1x FNA if nodule classified TR2 or less). FNA performed on most high grade nodule or if equal grade then largest nodule.
- No enlarged / suspicious neck lymphadenopathy on ultrasound.
- Patient willing to undergo thyroid nodule embolization in preference to other viable treatment options after discussion with Consultant ENT surgeon and / or Consultant treatment Radiologist. TAE can also be performed as...
- Patient able to lay on the angiography table flat with one or two pillows, and can lay comfortably with 30 degrees or less of head elevation for a minimum of two hours.
The study team makes the final eligibility decision.
Where it's taking place
- Reading, United Kingdom
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Reading, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.