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New treatment option for Mild Neurocognitive Disorder
Official title Deep rTMS for Mild Neurocognitive Disorder in Older Adults
ClinicalTrials.gov ID: NCT07038798
What this study is testing
- What it's testing
- This study aims to: (1) assess the feasibility and tolerability of three deep transcranial magnetic stimulation (dTMS) coils H1, H4, and H7 in older adults with mild neurocognitive disorder (mild NCD); and (2) evaluate changes in cognition through neuropsychological testing, brain activity through EEG, and mood and sleep through self-report questionnaires. Participants will be assigned to one of three arms: H1- coil vs.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 90
You may be able to join if
- 60 - 90 years old
- Able to provide informed consent to participate in the study
- Subjective concern of mild decline in cognitive function over the past year
- Mild impairment in cognitive performance
- Preserved independence in everyday activities
You likely can't join if
- Currently receiving treatment or subjective need for treatment for bipolar I or II disorder; psychotic disorder
- Active suicidal behavior
- Severe depression and/or anxiety
- Other neurological or psychiatric disorders accounting for the cognitive deficits
- Impairment in basic and/or instrumental activities of daily living
- Substance use disorder (other than tobacco use disorder) in the past 3 months before entering the study
See the full eligibility criteria
- 60 - 90 years old
- Able to provide informed consent to participate in the study
- Subjective concern of mild decline in cognitive function over the past year
- Mild impairment in cognitive performance
- Preserved independence in everyday activities
- Independently mobile (e.g., participants must be able to get in and out of a chair on their own)
- Participants will be required to be on stable dosages of other psychotropic medications for at least 4 weeks prior to screening
- Currently receiving treatment or subjective need for treatment for bipolar I or II disorder; psychotic disorder
- Active suicidal behavior
- Severe depression and/or anxiety
- Other neurological or psychiatric disorders accounting for the cognitive deficits
- Impairment in basic and/or instrumental activities of daily living
- Substance use disorder (other than tobacco use disorder) in the past 3 months before entering the study
- Traditional contraindications to rTMS: Intracranial or metal implants in the head or nearby regions, excluding the mouth, that cannot be safely removed; History of epilepsy or seizures; Active unstable medical condition...
- People with severe literacy, visual, or hearing issues that affect the ability to engage in the interviews
- People with recurring migraines or headaches (weekly or more)
- Frequent dizziness/vertigo
- Individuals residing beyond the borders of the Greater Hamilton Area and its neighbouring vicinities
The study team makes the final eligibility decision.
Where it's taking place
- Hamilton, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hamilton, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.