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New treatment option for Primary Ciliary Dyskinesia
Official title Thermal Spa Treatment and Improvement of Primary Ciliary Dyskinesia
ClinicalTrials.gov ID: NCT07029594
What this study is testing
- What it's testing
- The goal of this clinical trial is to evaluate whether a 3-week thermal spa treatment can improve quality of life and reduce ENT (ear, nose, and throat) symptoms in adults with Primary Ciliary Dyskinesia (PCD). PCD is a rare, chronic condition that affects the airways and often leads to persistent sinus, ear, and lung infections.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Confirmed diagnosis of Primary Ciliary Dyskinesia (PCD) based on electron microscopy analysis of ciliary ultrastructure and/or genetic testing (i.e...
- Age over 18 years.
- Stable maintenance treatment for at least 1 month prior to inclusion.
- Performance Status (PS) ≤ 1.
- Patient has received the study information sheet and signed the informed consent form.
You likely can't join if
- Participation in a thermal spa treatment within the past year.
- Severe general health deterioration or debilitating conditions.
- Severe or recent heart failure.
- Labile hypertension.
- Venous insufficiency or deep vein thrombosis within the past 3 months.
- Recent unhealed fracture.
See the full eligibility criteria
- Confirmed diagnosis of Primary Ciliary Dyskinesia (PCD) based on electron microscopy analysis of ciliary ultrastructure and/or genetic testing (i.e., two unambiguous mutations in genes known to be involved in PCD...
- Age over 18 years.
- Stable maintenance treatment for at least 1 month prior to inclusion.
- Performance Status (PS) ≤ 1.
- Patient has received the study information sheet and signed the informed consent form.
- Patient has valid health insurance coverage.
- Participation in a thermal spa treatment within the past year.
- Severe general health deterioration or debilitating conditions.
- Severe or recent heart failure.
- Labile hypertension.
- Venous insufficiency or deep vein thrombosis within the past 3 months.
- Recent unhealed fracture.
- Unhealed skin lesions (wounds, pressure sores, eczema).
- Contagious or progressive diseases.
- Recent cancer (less than 5 years).
- Ongoing or recent (within the past month) pulmonary or ENT exacerbation at inclusion.
- Ongoing treatment with immunomodulatory or immunosuppressive drugs (due to the risk of potentially severe opportunistic infections).
- Ongoing or recent (within the past month) extra-respiratory or ENT infectious flare-up.
- Positive pre-cure bacteriological testing for multidrug-resistant Pseudomonas aeruginosa, MRSA, Mycobacterium abscessus, or other multidrug-resistant pathogenic bacteria.
- Fever \> 38.5°C.
- Recently worsened dyspnea (\< 1 month).
- History of serious adverse effects or intolerance during a previous thermal spa treatment.
- Participation in another clinical trial with an exclusion period.
- Considered a vulnerable person, as defined by Articles L1121-5 to L1121-8 of the French Public Health Code: Pregnant women, women in labor, and breastfeeding mothers. Individuals deprived of liberty by judicial or...
The study team makes the final eligibility decision.
Where it's taking place
- Nice, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nice, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.