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New treatment option for Postoperative Pulmonary Complications (PPCs)
Official title Sigh Ventilation in Cardiac Surgery
ClinicalTrials.gov ID: NCT07024420
What this study is testing
- What it's testing
- The purpose of this trial is to investigate whether sigh ventilation strategy, combining sigh breaths, low tidal volume, and moderate PEEP levels, protects against major pulmonary complications within the first 7 postoperative days after cardiac surgery, as compared with conventional ventilation strategy with low tidal volume, and moderate PEEP levels.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 18 years of age or older;
- Elective cardiac surgery with cardiopulmonary bypass, aortic clamp and cardioplegia;
- Written informed consent is obtained from patients and/or their legal representatives.
You likely can't join if
- Emergence surgery;
- Left ventricular assist device implantation;
- Planned thoracotomy with one lung ventilation;
- Undergo concurrent surgical procedures outside cardiology;
- Neuromuscular illness;
- Mechanical ventilation within the last 2 weeks before surgery, include CPAP and NIV;
See the full eligibility criteria
- 18 years of age or older;
- Elective cardiac surgery with cardiopulmonary bypass, aortic clamp and cardioplegia;
- Written informed consent is obtained from patients and/or their legal representatives.
- Emergence surgery;
- Left ventricular assist device implantation;
- Planned thoracotomy with one lung ventilation;
- Undergo concurrent surgical procedures outside cardiology;
- Neuromuscular illness;
- Mechanical ventilation within the last 2 weeks before surgery, include CPAP and NIV;
- Preoperative shock;
- Preoperative Hypoxemia (PaO2\<60mmHg OR SpO2\<90% on ambient air);
- Preoperative left ventricular ejection fraction \< 40%;
- Systolic pulmonary artery pressure \> 50 mmHg.
The study team makes the final eligibility decision.
Where it's taking place
- Nanjing, Jiangsu, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nanjing, Jiangsu, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.