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Tests treatment safety and results for Etomidate Combined With Propofol
Official title Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery
ClinicalTrials.gov ID: NCT07019246
What this study is testing
What is EP mixture?
EP mixture is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for etomidate combined with propofol.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 to 80. Healthy volunteers may be eligible.
You may be able to join if
- ASA Ⅰ\~Ⅲ;
- BMI was 18-28 kg/m2;
- For elective abdominal surgery under intravenous general anesthesia;
- The expected duration of anesthesia was 1 to 4 hours.
You likely can't join if
- Septic shock and multiple organ failure diagnosed within 14 days;
- Hyperkalemia (serum potassium \>5.5mmol/L) within 48 hours;
- Stroke or transient ischemic attack within 3 months;
- Patients with unstable angina pectoris or myocardial infarction within 3 months; Arrhythmia requiring treatment was not treated or treatment did not...
- Patients with preoperative diagnosed diabetes mellitus and uncontrolled blood glucose; Diabetic complications were diagnosed before surgery...
- Severe liver and renal dysfunction;
See the full eligibility criteria
- ASA Ⅰ\~Ⅲ;
- BMI was 18-28 kg/m2;
- For elective abdominal surgery under intravenous general anesthesia;
- The expected duration of anesthesia was 1 to 4 hours.
- Septic shock and multiple organ failure diagnosed within 14 days;
- Hyperkalemia (serum potassium \>5.5mmol/L) within 48 hours;
- Stroke or transient ischemic attack within 3 months;
- Patients with unstable angina pectoris or myocardial infarction within 3 months; Arrhythmia requiring treatment was not treated or treatment did not meet expectations;
- Patients with preoperative diagnosed diabetes mellitus and uncontrolled blood glucose; Diabetic complications were diagnosed before surgery, including diabetic ketoacidosis, hyperosmolar coma, diabetes-related...
- Severe liver and renal dysfunction;
- Liver surgery, renal surgery, adrenal surgery, day surgery;
- Resting blood pressure ≥180/110 mmHg (2020 ISH hypertension guideline ≥ grade 3 hypertension); Or systolic blood pressure \<90mmHg or mean blood pressure \<65mmHg.
- Taking corticosteroids or other immunosuppressants for more than 10 days within 6 months or having a history of adrenal cortex suppression or immune system diseases;
The study team makes the final eligibility decision.
Where it's taking place
- Wuhan, Hubei, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Wuhan, Hubei, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.