Recruiting NA Genetic Predisposition to Disease

Tests treatment safety and results for Genetic Predisposition to Disease

Official title Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure

ClinicalTrials.gov ID: NCT07018128

What this study is testing

What it's testing
This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood pressure in individuals with hypertension.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 59. Healthy volunteers may be eligible.

You may be able to join if

  • Study 1:
  • Group of individuals with hypertension
  • Male or female
  • Aged between 18-59 years
  • Of Thai ethnicity

You likely can't join if

  • Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure
  • Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher
  • Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections
  • Group of individuals with normal blood pressure Inclusion Criteria:
  • Male or female
  • Aged between 18-59 years
See the full eligibility criteria
Who can join
  • Study 1:
  • Group of individuals with hypertension
  • Male or female
  • Aged between 18-59 years
  • Of Thai ethnicity
  • Diagnosed with hypertension, defined as having an SBP of 140 mmHg or higher, or a DBP of 90 mmHg or higher, or having previously been diagnosed with hypertension and currently taking antihypertensive medication
  • Originally from various regions of Thailand and currently residing in the eastern region
What rules you out
  • Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure
  • Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher
  • Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections
  • Group of individuals with normal blood pressure Inclusion Criteria:
  • Male or female
  • Aged between 18-59 years
  • Of Thai ethnicity
  • Does not have hypertension, defined as having an SBP below 130 mmHg and a DBP below 85 mmHg, with no prior diagnosis of hypertension and no history of taking antihypertensive medication
  • Originally from various regions of Thailand and currently residing in the eastern region Exclusion Criteria:
  • Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure
  • Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher
  • Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections Study 2: Inclusion Criteria:
  • Male or female, aged 35-59 years
  • Diagnosed with hypertension, with blood pressure levels above the normal range, defined as SBP of 130 mmHg or higher, or DBP of 85 mmHg or higher, and currently taking medication
  • Originally from various regions of Thailand and currently residing in the eastern region
  • Able to communicate effectively Exclusion Criteria:
  • Has respiratory diseases, cardiovascular diseases, cerebrovascular disease, kidney disease, cancer, or immune-related conditions such as allergies, autoimmune diseases (e.g., SLE), immunodeficiency, or rheumatoid...
  • Is obese, defined as having a body mass index (BMI) of 30 kg/m² or higher
  • Has a fever or is currently infected, such as with COVID-19, the flu, or other infectious diseases
  • Is currently pregnant, breastfeeding, or has a history of pregnancy within the 6 months prior to participating in the study

The study team makes the final eligibility decision.

Where it's taking place

  • MueangChonburi, Changwat Chon Buri, Thailand

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 59 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include MueangChonburi, Changwat Chon Buri, Thailand. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.