Recruiting NA Opioid Use

New treatment option for Opioid Use

Official title Effect of MGRNOX-Guided General Anesthesia on Opioid Consumption in Patients

ClinicalTrials.gov ID: NCT07004686

What this study is testing

What it's testing
1. Pain management is a crucial part of general anesthesia surgery.
  • Which group you join is decided by chance.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 64

You may be able to join if

  • Age ≥18 years old and \< 65 years old;
  • American Society of Anesthesiologists (ASA) class I-II;
  • Scheduled to undergo elective laparoscopic cholecystectomy undergeneral anesthesia (without epidural anesthesia, local blocks, or infiltration)

You likely can't join if

  • Pregnancy or lactation period;
  • BMI ≥35 kg/m² or \<18.5 kg/m²;
  • Anticipated difficult airway;
  • Previous diagnosis of hypertension;
  • History of drug or alcohol abuse within the past 6 months;
  • Preoperative acute or chronic pain history (routine preoperative use of opioid or non-opioid analgesics), peripheral or central nervous...
See the full eligibility criteria
Who can join
  • Age ≥18 years old and \< 65 years old;
  • American Society of Anesthesiologists (ASA) class I-II;
  • Scheduled to undergo elective laparoscopic cholecystectomy undergeneral anesthesia (without epidural anesthesia, local blocks, or infiltration)
What rules you out
  • Pregnancy or lactation period;
  • BMI ≥35 kg/m² or \<18.5 kg/m²;
  • Anticipated difficult airway;
  • Previous diagnosis of hypertension;
  • History of drug or alcohol abuse within the past 6 months;
  • Preoperative acute or chronic pain history (routine preoperative use of opioid or non-opioid analgesics), peripheral or central nervous system-related disorders;
  • Definitively diagnosed psychiatric disorders or other neuropsychiatric conditions severely affecting cognitive judgment, history of psychotropic medication use;
  • Allergy or intolerance to anesthetic agents;
  • Baseline mean arterial pressure (MAP) \ 120 mmHg; baseline heart rate (HR) \ 90 bpm (Baseline values defined as first measurement taken in the ward after admission);
  • History of severe underlying diseases (untreated or ongoing peripheral/central cardiovascular diseases, severe hepatic disorders with elevated bilirubin/INR or hypoalbuminemia, severe renal diseases with elevated...
  • Implanted pacemaker, chronic arrhythmia, preoperative use of prescribed anticholinergics, α2-adrenergic agonists, beta-1 adrenergic antagonists, or antiarrhythmic medications.

The study team makes the final eligibility decision.

Where it's taking place

  • Shenzhen, Guangdong, China

Compensation & support

Compensation mentioned.

ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.

Questions & answers

Do participants get paid in this trial?

This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 64 years. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Shenzhen, Guangdong, China. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.