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Official title Role of Inferior Colliculi in Auditory Hallucinations
ClinicalTrials.gov ID: NCT07003529
What this study is testing
- What it's testing
- The neural basis of auditory hallucinations (AH) in patients with schizophrenia is poorly characterized. Functional imaging studies investigate either the "state" dimension (i.e., the measurement of changes in brain area activation at the precise moment of AH onset) or the "trait" dimension (i.e., the neural correlates of the propensity to hallucinate).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- The patient must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
- DSM-5 diagnosis of schizophrenic disorder (based on clinical assessment and confirmed by the MINI 7.0 interview)
- Patient with a schizophrenic disorder lasting ≤ 20 years
- Patient treated in a psychiatric unit as an inpatient (in non-specialized care) or outpatient or under a mandatory ambulatory psychiatric care...
You likely can't join if
- The patient is under safeguard of justice or state guardianship
- Contraindications to magnetic resonance imaging, including severe claustrophobia, based on clinical judgment.
- Congenital or acquired deafness
- Suicide risk, based on clinical judgment
- Patient with moderate to severe intellectual disability, based on medical records
- Patient with moderate to severe neurocognitive disorders, based on medical records
See the full eligibility criteria
- The patient must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
- DSM-5 diagnosis of schizophrenic disorder (based on clinical assessment and confirmed by the MINI 7.0 interview)
- Patient with a schizophrenic disorder lasting ≤ 20 years
- Patient treated in a psychiatric unit as an inpatient (in non-specialized care) or outpatient or under a mandatory ambulatory psychiatric care programme
- Clinical condition compatible with imaging based on clinical judgment
- Ability to understand, write, and read French Specific for the group (SCZ+/HA+) Patient with a PANSS score (question P3 regarding hallucinations) ≥ 4 (corresponds to PANSS (P3) 4, 5, 6, and 7 patients) AND having...
- Patient with a PANSS score (question P3 regarding hallucinations) = 1) AND having not experienced any hallucinations in the past 15 days.
- The patient is under safeguard of justice or state guardianship
- Contraindications to magnetic resonance imaging, including severe claustrophobia, based on clinical judgment.
- Congenital or acquired deafness
- Suicide risk, based on clinical judgment
- Patient with moderate to severe intellectual disability, based on medical records
- Patient with moderate to severe neurocognitive disorders, based on medical records
- Patient receiving anticholinergic therapy (biperiden-Akineton, trihexyphenidyl-Artane, tropatepine-Lepticur)
- Patient participating in an treatment study involving a drug or medical device, or a Category 1 RIPH within 3 months prior to inclusion
- Person under judicial protection
- Pregnant, parturient, or breastfeeding woman
- Person unable to express consent
The study team makes the final eligibility decision.
Where it's taking place
- Nîmes, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nîmes, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.