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New treatment option for Gastroesophageal Reflux Disease
Official title Clinical Trial for the Comparative Evaluation of Acid Suppression and Symptom Management of Gastroesophageal Reflux Disease With the Administration of Tegoprazan or Pantoprazole
ClinicalTrials.gov ID: NCT06991348
What this study is testing
What is Tegoprazan?
Tegoprazan is an investigational medicine, given as an once-daily, being studied as a potential treatment for gastroesophageal reflux disease.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The objective of this clinical trial is to compare which of the two drugs best resolves symptoms in patients diagnosed with erosive and non-erosive gastroesophageal reflux disease, adult males and females. The main question is What is the proportion of patients with resolution of the main symptoms of gastroesophageal reflux disease at four weeks of treatment with pantoprazole vs tegoprazan.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- With endoscopic diagnosis of GERD or NERD (endoscopy ≤ 15 days old)
- With positive impedance pHmetry results (pHmetry ≤ 15 days old)
- With recurrent symptoms of heartburn and regurgitation for a previous period ≥ 3 months old
You likely can't join if
- With known hypersensitivity to tegoprazan, pantoprazole, or any of the components of each formulation
- people with concomitant administration of atazanavir, nelfinavir or rilpivirine
- Nephropathic and/or hepatopathic people (including non-alcoholic hepatitis)
- people with upper gastrointestinal tract bleeding
- people with gastric and/or duodenal ulcer 2 months prior to screening
- people with a history of esophageal or gastric surgery
The study team makes the final eligibility decision.
Where it's taking place
- Mexico City, Mexico City, Mexico
- Boca del Río, Veracruz, Mexico
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Mexico City, Mexico City, Mexico; Boca del Río, Veracruz, Mexico. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.