BridgeMD
New treatment option for We Are Not Studying a Disease or Condition
Official title Transcranial Direct Current Stimulation and Modulation of Affect and Pain
ClinicalTrials.gov ID: NCT06989749
What this study is testing
- What it's testing
- This double-blind randomized crossover study aims to examine the effects of left primary motor cortex (M1) tDCS on evoked thermal pain perception, pain-related decision making, and placebo effects by manipulated pain and monetary offers accepted by others. The investigators plan to collect data for up to 50 participants who undergo four separate sessions: an initial pain calibration session and three experimental sessions with either anodal, cathodal, or sham tDCS.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55. Healthy volunteers may be eligible.
You may be able to join if
- ages 18-55
- Participants must be capable of performing experimental tasks (e.g., are able to read)
- Fluent or native speakers of English
You likely can't join if
- No self-reported current or history of depression, bipolar disorder, or other psychiatric diagnosis.
- No self-reported current seizure disorder (i.e., seizure within past 10 years)
- No history of stroke or other major neurological diagnosis.
- No self-reported current chronic pain, or acute pain within three months of the study period.
- No current migraine disorder (i.e., 15 headache days or more in 1 month).
- No use of central nervous system-effective medication or other medication for neurological/psychiatric treatment. No self-reported substance abuse...
See the full eligibility criteria
- ages 18-55
- Participants must be capable of performing experimental tasks (e.g., are able to read)
- Fluent or native speakers of English
- No self-reported current or history of depression, bipolar disorder, or other psychiatric diagnosis.
- No self-reported current seizure disorder (i.e., seizure within past 10 years)
- No history of stroke or other major neurological diagnosis.
- No self-reported current chronic pain, or acute pain within three months of the study period.
- No current migraine disorder (i.e., 15 headache days or more in 1 month).
- No use of central nervous system-effective medication or other medication for neurological/psychiatric treatment. No self-reported substance abuse within the last six months.
- No contraindication to MRI or tDCS (e.g., pregnancy, claustrophobia, pacemakers, ear/cochlear implants, shrapnel injuries, clips, or other ferromagnetic/electrical objects/devices, diagnosed brain abnormality such as...
- No contraindications for induced pain (e.g., no heart disease, high blood pressure, heart surgery, heart problems of any kind, severe asthma, respiratory problems of any kind, fibromyalgia, Raynaud's Syndrome or...
The study team makes the final eligibility decision.
Where it's taking place
- Hanover, New Hampshire, United States
Compensation & support
A stipend or compensation may be offered.
Compensation likely.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hanover, New Hampshire, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.