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Compares treatment options for Community Acquired Pneumonia (CAP)
Official title Comparing Antibiotic Treatment Strategies for Children With Pneumonia in Outpatient Settings: (STAMPP)
ClinicalTrials.gov ID: NCT06986148
What this study is testing
- What it's testing
- The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring that children diagnosed with community-acquired pneumonia get better from their illness. The main aims of this study are: To compare the effectiveness of SNAP versus immediate antibiotic prescribing in children with mild community-acquired pneumonia (CAP) To identify which patient groups benefit most from the SNAP strategy To identify factors that shape implementation of each prescribing strategy.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 71
You may be able to join if
- Aims 1 and 2:
- Presenting with signs and symptoms of lower respiratory tract infection
- Diagnosed with community-acquired pneumonia (CAP) by a clinician
- The treating clinician intends to prescribe antibiotics for CAP, AND
- Well enough, as determined by the clinician at the time of the study enrollment visit, to be managed as an outpatient.
You likely can't join if
- Aims 1 and 2:
- Hospitalization within the previous 7 days
- Oxygen saturation below 90%, if measured
- Incomplete immunization status (e.g., lacking at least 3 doses of the pneumococcal vaccines, typically given as part of the 2-, 4-, and 6-month...
- Chronic medical conditions that increase the risk of bacterial CAP (e.g., chronic lung disease, cystic fibrosis, sickle cell disease),
- Substantially immunocompromised status (e.g., immunodeficiency, active cancer treatment, organ transplant with concurrent immunosuppressive agents)
See the full eligibility criteria
- Aims 1 and 2:
- Presenting with signs and symptoms of lower respiratory tract infection
- Diagnosed with community-acquired pneumonia (CAP) by a clinician
- The treating clinician intends to prescribe antibiotics for CAP, AND
- Well enough, as determined by the clinician at the time of the study enrollment visit, to be managed as an outpatient.
- Aim 3:
- Parent/guardian of child enrolled in the trial, OR
- Clinician who makes prescribing decision at the study site, OR
- Other practice-based parties (e.g. nurses, pharmacists, medical assistants, practice leaders) at study sites who can comment on the implementation of each prescribing strategy.
- Aims 1 and 2:
- Hospitalization within the previous 7 days
- Oxygen saturation below 90%, if measured
- Incomplete immunization status (e.g., lacking at least 3 doses of the pneumococcal vaccines, typically given as part of the 2-, 4-, and 6-month vaccinations)
- Chronic medical conditions that increase the risk of bacterial CAP (e.g., chronic lung disease, cystic fibrosis, sickle cell disease),
- Substantially immunocompromised status (e.g., immunodeficiency, active cancer treatment, organ transplant with concurrent immunosuppressive agents)
- Receipt of oral or parenteral antibiotics within the previous 7 days
- Diagnosis of complicated pneumonia (e.g., empyema, lung abscess)
- Known bacterial source of infection warranting immediate antibiotics
- Pneumonia diagnosis within the previous 6 months, OR
- Prior enrollment in the trial
- Inability of the parent or guardian to speak English or Spanish
- Aim 3:
- Inability of the parent or guardian to speak English
The study team makes the final eligibility decision.
Where it's taking place
- Atlanta, Georgia, United States
- Chicago, Illinois, United States
- Philadelphia, Pennsylvania, United States
- Salt Lake City, Utah, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 months to 71 months. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Atlanta, Georgia, United States; Chicago, Illinois, United States; Philadelphia, Pennsylvania, United States; Salt Lake City, Utah, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.