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New treatment option for Cough
Official title Dexmedetomidine, Magnesium Sulphate and Lidocaine for Cough Suppression After General Anesthesia
ClinicalTrials.gov ID: NCT06979141
What this study is testing
What is Dexmedetomidine?
Dexmedetomidine is an investigational medicine, being studied as a potential treatment for cough.
Also referred to as dex.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this prospective randomized controlled double-blinded study is to compare the efficacy of dexmedetomidine, MgSO4 and lidocaine for cough suppression during general anesthetic emergence as regard number and severity.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 60
You may be able to join if
- Aged 21-60 years.
- Both genders.
- Body mass index \< 30 kg/ m2
- American Society of Anesthesiology (ASA) physical status I-II.
- Mallampati score class I or II.
You likely can't join if
- Known allergy to study drugs.
- History of psychiatric illness.
- Patients with major organ diseases.
- Pre-existing neurological deficits.
- Body mass index \>30 kg/m2.
- Active airway infection or history of tracheal and laryngeal surgery.
See the full eligibility criteria
- Aged 21-60 years.
- Both genders.
- Body mass index \< 30 kg/ m2
- American Society of Anesthesiology (ASA) physical status I-II.
- Mallampati score class I or II.
- Patients undergoing surgery under general anesthesia.
- Known allergy to study drugs.
- History of psychiatric illness.
- Patients with major organ diseases.
- Pre-existing neurological deficits.
- Body mass index \>30 kg/m2.
- Active airway infection or history of tracheal and laryngeal surgery.
- Lower esophageal sphincter incompetence (and reflux).
- Increased intracranial and intraocular pressure.
- Use of cough-inducing medications
- Pregnant, and lactating women.
The study team makes the final eligibility decision.
Where it's taking place
- Asyut, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Asyut, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.