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New treatment option for Delirium
Official title Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
ClinicalTrials.gov ID: NCT06969287
What this study is testing
What is Fluvoxamine?
Fluvoxamine is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for delirium.
Also referred to as Oral Fluvoxamine 100 mg capsules (immediate release).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The investigation will establish biological plausibility and infrastructure required for a multisite clinical trial evaluating the re-purposing of fluvoxamine to mitigate postoperative delirium risk in geriatric patients undergoing non-cardiac non-intracranial surgery.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 and older
You may be able to join if
- English-speaking
- elective non-cardiac or non-intracranial surgery requiring at least a 2-day hospital length of stay
You likely can't join if
- Received investigational drug within the last 7 weeks
- lack of capacity to provide informed consent
- prior known intolerance or allergy to SSRIs or fluvoxamine
- planned postoperative ventilation
- drug or alcohol dependence
- preoperative use of non-NSAID medications with drug-drug interactions of Class X (Avoid Combination) or D (Consider Therapy Modification)
See the full eligibility criteria
- English-speaking
- elective non-cardiac or non-intracranial surgery requiring at least a 2-day hospital length of stay
- Received investigational drug within the last 7 weeks
- lack of capacity to provide informed consent
- prior known intolerance or allergy to SSRIs or fluvoxamine
- planned postoperative ventilation
- drug or alcohol dependence
- preoperative use of non-NSAID medications with drug-drug interactions of Class X (Avoid Combination) or D (Consider Therapy Modification)
- risk of serotonin syndrome (St John's Wort, SSRIs, or TCA)
The study team makes the final eligibility decision.
Where it's taking place
- St Louis, Missouri, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include St Louis, Missouri, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.