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New treatment option for Periodontitis
Official title Comparative Effects of Two Oral Antiseptics Used as an Adjuvant in the Treatment of Periodontitis
ClinicalTrials.gov ID: NCT06967402
What this study is testing
- What it's testing
- The focus of this study is on two types of mouthwashes - one containing a chlorhexidine (CHX) at 0.2% (CHX), and the other one containing CHX at a lower concentration of 0.12% with cetylpyridinium chloride (CPC). Both mouthwashes are used to help in the treatment of gum disease.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Consenting patients with at least 6 evaluable teeth in each quadrant, including minimum 1 molar and 1 premolar.
- Generalized stage II-III periodontitis patients.
- Baseline BOP \> 25%.
- No known allergy or adverse effects to CHX or CPC
- Non-smokers, non-orthodontic patients, no concurrent or past antibiotics/medication known to affect periodontal status (i.e. calcium antagonists...
You likely can't join if
- Unable to provide written consent.
- Non-compliant study procedures.
- Patients with medical (including psychiatric) and pharmacotherapeutic histories that, in the investigator's opinion, may compromise the protocol.
- Patients requiring antibiotics prophylaxis for dental procedures.
- Patients with self-reported pregnancy or patients who are breastfeeding.
- Patients with history of use of systemic antibiotics, in combination with any form of periodontal treatment, within the past 3 months.
See the full eligibility criteria
- Consenting patients with at least 6 evaluable teeth in each quadrant, including minimum 1 molar and 1 premolar.
- Generalized stage II-III periodontitis patients.
- Baseline BOP \> 25%.
- No known allergy or adverse effects to CHX or CPC
- Non-smokers, non-orthodontic patients, no concurrent or past antibiotics/medication known to affect periodontal status (i.e. calcium antagonists, phenytoin)/anti-inflammatory therapy (i.e. NASIDs) in the last 3 months...
- ASA class I-II patients.
- Either non-diabetic or with controlled diabetes (HbA1C\<7).
- Normal/Elevated blood pressure (AHA - Systolic \<130mmHg; Diastolic \<80mmHg).
- No radiation/chemotherapy in the past 5 years
- No immunosuppression including drug induced immunosuppression.
- No participation in other clinical studies in the last 4 weeks.
- No administration of CHX or CPC in the last 3 months
- No periodontal treatment in the last 3 months.
- Unable to provide written consent.
- Non-compliant study procedures.
- Patients with medical (including psychiatric) and pharmacotherapeutic histories that, in the investigator's opinion, may compromise the protocol.
- Patients requiring antibiotics prophylaxis for dental procedures.
- Patients with self-reported pregnancy or patients who are breastfeeding.
- Patients with history of use of systemic antibiotics, in combination with any form of periodontal treatment, within the past 3 months.
- Patients with uncontrolled endocrine disease.
- Patients who are not compliant with the review protocol, leading to deviation of more than 1 week.
- Patients requiring the admission of systemic antibiotics, in combination with any form of dental treatment, during the study period.
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.