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New treatment option for Stent Related Symptoms
Official title Comparison of Alpha Blockers (Terazosin and Tamsulosin) in Reducing Ureteral Stent Related Symptoms
ClinicalTrials.gov ID: NCT06966804
What this study is testing
What is Terazosin?
Terazosin is an investigational medicine, being studied as a potential treatment for stent related symptoms.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to compare how well Terazosin, Tamsulosin and standard care (no alpha-blocker) reduce urinary symptoms after ureteral stent placement. This trial also learn about the safety of these two study medications.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Malaysian age 18 years old and above.
- Able to provide written informed consent to participate in the trial.
- Willing to comply with study procedures.
- Unilateral intracorporeal lithotripsy procedure with ureteral stent placement for uncomplicated ureteric or renal calculi
You likely can't join if
- Known comorbidity that increase the risk of complication
- Prostate pathology: Benign prostate hyperplasia, prostatitis, prostatic carcinoma
- Bladder pathology: Bladder tumor, stone, overactive bladder
- Ureteral abnormality/ trauma, urethral stricture
- Concomitant urinary tract infection
- Orthostatic hypotension
See the full eligibility criteria
- Malaysian age 18 years old and above.
- Able to provide written informed consent to participate in the trial.
- Willing to comply with study procedures.
- Unilateral intracorporeal lithotripsy procedure with ureteral stent placement for uncomplicated ureteric or renal calculi
- Known comorbidity that increase the risk of complication
- Prostate pathology: Benign prostate hyperplasia, prostatitis, prostatic carcinoma
- Bladder pathology: Bladder tumor, stone, overactive bladder
- Ureteral abnormality/ trauma, urethral stricture
- Concomitant urinary tract infection
- Orthostatic hypotension
- Solitary kidney
- Previous pelvic/ gynaecological surgery
- Patient is concomitantly receiving treatment from a pain clinic for chronic pain management.
- Pregnancy (for women of childbearing potential)
- Known history of allergic reactions to tamsulosin or terazosin
- Patient is concomitantly taking warfarin or H2 receptor blockers
- Patients with clinical condition(s) judged by the researcher/ clinician to be unsuitable for participation in the study
The study team makes the final eligibility decision.
Where it's taking place
- Alor Star, Kedah, Malaysia
- George Town, Pulau Pinang, Malaysia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Alor Star, Kedah, Malaysia; George Town, Pulau Pinang, Malaysia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.