Recruiting NA Intolerance of Uncertainty

New treatment option for Intolerance of Uncertainty

Official title Test of Target Engagement of Ambiguity Aversion

ClinicalTrials.gov ID: NCT06962527

What this study is testing

What it's testing
The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.
  • Which group you join is decided by chance.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 25 to 60. Healthy volunteers may be eligible.

You may be able to join if

  • Ages 25 to 60
  • Right-handed
  • Ability to read and write English
  • Capacity to provide informed consent
  • Intolerance of uncertainty score ≥ -0.5 standard deviation below the mean (31st percentile)

You likely can't join if

  • Personal history of psychosis, mania, or hypomania
  • Personal history of autism spectrum disorder
  • IQ \< 80 as determined by the Wechsler Test of Adult Reading
  • Head injury with greater than 120 seconds loss of consciousness
  • Neurological condition (e.g., epilepsy, Parkinson's, cerebral palsy, history of stroke)
  • Currently pregnant
See the full eligibility criteria
Who can join
  • Ages 25 to 60
  • Right-handed
  • Ability to read and write English
  • Capacity to provide informed consent
  • Intolerance of uncertainty score ≥ -0.5 standard deviation below the mean (31st percentile)
What rules you out
  • Personal history of psychosis, mania, or hypomania
  • Personal history of autism spectrum disorder
  • IQ \< 80 as determined by the Wechsler Test of Adult Reading
  • Head injury with greater than 120 seconds loss of consciousness
  • Neurological condition (e.g., epilepsy, Parkinson's, cerebral palsy, history of stroke)
  • Currently pregnant
  • Use of any implanted electrical device (e.g., pacemaker, spinal stimulator, vagal nerve stimulator, Inspire sleep apnea device, etc.).

The study team makes the final eligibility decision.

Where it's taking place

  • Chicago, Illinois, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 25 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Chicago, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.