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New treatment option for Periodontitis
Official title Adjunctive Effect of Erythritol on Pocket Closure Rates
ClinicalTrials.gov ID: NCT06958874
What this study is testing
- What it's testing
- This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants with deep gum pockets (4 mm or more) receive standard treatment alone or standard treatment plus cleaning with erythritol powder.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 and older
You may be able to join if
- Adults aged 18 years or older
- Diagnosed with stage 3 or 4 periodontitis according to the 2017 classification
- Presence of at least 12 natural teeth
- Presence of periodontal pockets with probing depth ≥ 4 mm in non-adjacent teeth
- Good general health or stable systemic conditions (e.g., controlled diabetes)
You likely can't join if
- Use of antibiotics or anti-inflammatory drugs within 3 months prior to treatment
- Periodontal treatment in the previous 6 months
- Pregnancy or breastfeeding
- Current smokers of more than 10 cigarettes per day
- Allergies or intolerance to erythritol or any materials used in the treatment
- Systemic diseases or conditions that could influence periodontal healing (e.g., uncontrolled diabetes, immunodeficiency)
See the full eligibility criteria
- Adults aged 18 years or older
- Diagnosed with stage 3 or 4 periodontitis according to the 2017 classification
- Presence of at least 12 natural teeth
- Presence of periodontal pockets with probing depth ≥ 4 mm in non-adjacent teeth
- Good general health or stable systemic conditions (e.g., controlled diabetes)
- Use of antibiotics or anti-inflammatory drugs within 3 months prior to treatment
- Periodontal treatment in the previous 6 months
- Pregnancy or breastfeeding
- Current smokers of more than 10 cigarettes per day
- Allergies or intolerance to erythritol or any materials used in the treatment
- Systemic diseases or conditions that could influence periodontal healing (e.g., uncontrolled diabetes, immunodeficiency)
- Use of medications known to affect periodontal tissues (e.g., phenytoin, cyclosporine, calcium channel blockers)
The study team makes the final eligibility decision.
Where it's taking place
- L’Aquila, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include L’Aquila, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.