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New treatment option for Acute Myocardial Infarction
Official title Stellate Ganglion Morphine Infiltration on Myocardial Ischemia-Reperfusion Injury
ClinicalTrials.gov ID: NCT06947135
What this study is testing
What is Morphine?
Morphine is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for acute myocardial infarction.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion injury in AMI patients. It will also assess the safety of injecting morphine around the stellate ganglion via ultrasound guidance.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Aged ≥18 years, Male or Female.
- Acute ST-segment elevation myocardial infarction (STEMI) patients planned for percutaneous coronary intervention (PCI). Acute STEMI is defined as...
- Within 24 hours of the onset of infarct-related chest pain.
- Obtaining informed consent from the patient and their family.
You likely can't join if
- Patients with severe complications of myocardial infarction, such as uncontrollable acute left heart failure and pulmonary edema, severe cardiogenic...
- Patients with old myocardial infarction, or cardiomyopathy, or malignant arrhythmias controlled by antiarrhythmic drugs;
- Patients with coagulation disorders due to systemic diseases and those who are currently using anticoagulants and are not suitable for injection;
- Patients allergic to opioids or with a history of opioid addiction and those participating in other clinical studies;
- Pregnant or breastfeeding women;
- Patients with severe organ dysfunction or failure, such as liver failure, renal failure, and respiratory failure;
See the full eligibility criteria
- Aged ≥18 years, Male or Female.
- Acute ST-segment elevation myocardial infarction (STEMI) patients planned for percutaneous coronary intervention (PCI). Acute STEMI is defined as: electrocardiogram shows ST-segment elevation ≥0.2 mV in two or more...
- Within 24 hours of the onset of infarct-related chest pain.
- Obtaining informed consent from the patient and their family.
- Patients with severe complications of myocardial infarction, such as uncontrollable acute left heart failure and pulmonary edema, severe cardiogenic shock after cardiopulmonary resuscitation, severe mechanical...
- Patients with old myocardial infarction, or cardiomyopathy, or malignant arrhythmias controlled by antiarrhythmic drugs;
- Patients with coagulation disorders due to systemic diseases and those who are currently using anticoagulants and are not suitable for injection;
- Patients allergic to opioids or with a history of opioid addiction and those participating in other clinical studies;
- Pregnant or breastfeeding women;
- Patients with severe organ dysfunction or failure, such as liver failure, renal failure, and respiratory failure;
- Patients with severe infections;
- Patients with severe mental illness that cannot cooperate and those taking antipsychotic drugs;
- Other patients considered unsuitable for this study by the researchers.
The study team makes the final eligibility decision.
Where it's taking place
- Hefei, Anhui, China
- Changsha, Hunan, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hefei, Anhui, China; Changsha, Hunan, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.