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New treatment option for Wilson Disease
Official title Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity
ClinicalTrials.gov ID: NCT06945081
What this study is testing
- What it's testing
- Wilson's disease is a genetic disorder, resulting from an anomaly present on the ATP7B gene located on chromosome 13, causing a progressive accumulation of copper in various organs such as the liver, nervous system and cornea, leading to various hepatic and neurological disorders and a systemic evolution. Currently, the first-line treatment for this disease is D-Penicillamine, which acts by chelation and promotes copper excretion through the urine.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 and older. Healthy volunteers may be eligible.
You may be able to join if
- Diseased patients :
- Patient over 12 years old
- Patient with Wilson's disease confirmed by genetic analysis
- Patient followed up in the Wilson's Disease Reference Center for his care
- Patient treated with D-Penicillamine
You likely can't join if
- All patients:
- Patient not taking a treatment (at investigator's discretion) that may modify skin elasticity
- Patient with pathological lesion(s) on forearm or cheek
- Patient with a potentially active/rejuvenative forearm or cheek treatment
- Patient having applied cream and/or make-up to the areas to be molded (forearm and cheek)
- Patient under guardianship
See the full eligibility criteria
- Diseased patients :
- Patient over 12 years old
- Patient with Wilson's disease confirmed by genetic analysis
- Patient followed up in the Wilson's Disease Reference Center for his care
- Patient treated with D-Penicillamine
- Patient with no other known elastic tissue pathology Healthy volunteers :
- Patient over 12 years old
- Patient followed up in the dermatology department of St Etienne University Hospital
- Patient matched on sex and age with a patient from the "Wilson's disease" group
- Patient with no elastic tissue pathology All patients :
- Patient affiliated to a national social security
- Patient with written informed consent
- All patients:
- Patient not taking a treatment (at investigator's discretion) that may modify skin elasticity
- Patient with pathological lesion(s) on forearm or cheek
- Patient with a potentially active/rejuvenative forearm or cheek treatment
- Patient having applied cream and/or make-up to the areas to be molded (forearm and cheek)
- Patient under guardianship
- Patient unable to follow study procedures
- Pregnant or breast-feeding women
The study team makes the final eligibility decision.
Where it's taking place
- Bron, France
- Saint-Etienne, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bron, France; Saint-Etienne, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.