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New treatment option for Idiopathic Inflammatory Demyelinating Disorders of the Central Nervous...
Official title Transcranial Electrical Stimulation for Treating Chronic Pain in Inflammatory Demyelinating Diseases
ClinicalTrials.gov ID: NCT06942611
What this study is testing
- What it's testing
- Non-invasive neurostimulation can effectively improve patients' symptoms and has shown good therapeutic efficacy in alleviating the symptoms of IIDDs (Inflammatory Immune-mediated Demyelinating Diseases). However, some patients have not achieved the desired results, which may be due to individual differences in neural responsiveness .
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Patients diagnosed with neuromyelitis optica spectrum disorder, multiple sclerosis, or other central nervous system inflammatory demyelinating...
- Numeric Rating Scale (NRS) pain score ≥4;
- Age between 18 and 65 years, regardless of gender;
- Stable dose of immunosuppressive therapy for at least one month;
- EDSS score ≤6;
You likely can't join if
- A history of relapse within the past month;
- Recent medication adjustments or treatment with modified electroconvulsive therapy, transcranial magnetic stimulation, or other neurostimulation...
- Participation in any other clinical trial within the past month or currently participating in another clinical trial;
- Presence of cochlear implants, pacemakers, or implanted stimulators in the brain;
- Skin integrity at the electrode placement site is compromised, or allergy to electrode gel or adhesive;
- A history of epilepsy, hydrocephalus, central nervous system tumors, brain injury, or intracranial infections;
See the full eligibility criteria
- Patients diagnosed with neuromyelitis optica spectrum disorder, multiple sclerosis, or other central nervous system inflammatory demyelinating diseases that meet the diagnostic criteria;
- Numeric Rating Scale (NRS) pain score ≥4;
- Age between 18 and 65 years, regardless of gender;
- Stable dose of immunosuppressive therapy for at least one month;
- EDSS score ≤6;
- Right-handed;
- Agree to participate and sign the informed consent form.
- A history of relapse within the past month;
- Recent medication adjustments or treatment with modified electroconvulsive therapy, transcranial magnetic stimulation, or other neurostimulation techniques within the past month;
- Participation in any other clinical trial within the past month or currently participating in another clinical trial;
- Presence of cochlear implants, pacemakers, or implanted stimulators in the brain;
- Skin integrity at the electrode placement site is compromised, or allergy to electrode gel or adhesive;
- A history of epilepsy, hydrocephalus, central nervous system tumors, brain injury, or intracranial infections;
- Pregnant or breastfeeding women, or those planning to become pregnant in the near future;
- A score of ≥3 on item 3 (suicide item) of the HDRS-17, or a history of severe psychiatric disorders;
- Presence of severe or unstable organic diseases;
- Poor patient compliance preventing cooperation with treatment, follow-up, or clinical, EEG, and imaging data collection;
- Any other situation deemed unsuitable for participation in the study by the investigator.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.