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New treatment option for Postural Orthostatic Tachycardia Syndrome (POTS)
Official title Counterpressure Maneuvers in Postural Orthostatic Tachycardia Syndrome
ClinicalTrials.gov ID: NCT06936319
What this study is testing
- What it's testing
- The present study evaluates whether performing a 14-days counter pressure maneuvers (CPM)-biofeedback training improves the symptomatic burden (primary objective) and secondarily the interference of POTS symptoms with daily activities, fatigue, and health-related quality of life of individuals with POTS compared to best clinical practice non-pharmacological measures. Secondary in-laboratory objectives are to assess the influence of CPM on the supine-to-standing heart rate (HR) and blood pressure (BP) changes as well as on the severity of orthostatic intolerance after performing CPM for two minutes compared to a baseline (intervention-free) active standing test, and to assess the safety and tolerability of CPM-biofeedback training in individuals with POTS.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- POTS diagnosis
- 18 to 80 years of age at time of consent
- stable medication in the seven days prior to the baseline visit
- able to provide written informed consent
You likely can't join if
- participation in other treatment trials
- pregnant or breastfeeding females
- on treatment with vasoactive medications including medications for heart rate control
- acute infections at the time of enrolment or in the two weeks before
- acute pain
- surgery in the last three months
See the full eligibility criteria
- POTS diagnosis
- 18 to 80 years of age at time of consent
- stable medication in the seven days prior to the baseline visit
- able to provide written informed consent
- participation in other treatment trials
- pregnant or breastfeeding females
- on treatment with vasoactive medications including medications for heart rate control
- acute infections at the time of enrolment or in the two weeks before
- acute pain
- surgery in the last three months
- inability or contraindication for performing hip and knee flexion, hip adduction or squatting
- inability to stand for at least two minutes
- Any other cardiological, internal, psychiatric or neurological condition, which may prevent engagement in the sturdy procedures in the judgement of the investigator
The study team makes the final eligibility decision.
Where it's taking place
- Innsbruck, Tyrol, Austria
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Innsbruck, Tyrol, Austria. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.