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New treatment option for Oral Immunotherapy for Food Allergy
Official title The NACHO Trial (Nut Allergy Children OIT)
ClinicalTrials.gov ID: NCT06930950
What this study is testing
- What it's testing
- Most food allergies that begin in early childhood are mild and resolve by school age, but nut allergies persist in about 80-90% of individuals into adulthood. The consumption of nuts, particularly cashew nuts, has increased dramatically in Finland in the 21st century, leading to a rise in severe allergic reactions to cashew nuts among young children.
- Time commitment: about 4 years
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 1 to 17
You may be able to join if
- Age 6 months - 17 years
- Sensitization to cashew nut (allergen-specific IgE or positive skin PRICK test)
- Positive oral food challenge for cashew nut
You likely can't join if
- Poor adherence
- Uncontrolled or severe asthma
- Uncontrolled active or severe or atopic dermatitis
- Chronic urticaria
- Eosinophilic esophagitis or other gastrointestinal eosinophilic disorders
- Active malignant neoplasia
See the full eligibility criteria
- Age 6 months - 17 years
- Sensitization to cashew nut (allergen-specific IgE or positive skin PRICK test)
- Positive oral food challenge for cashew nut
- Poor adherence
- Uncontrolled or severe asthma
- Uncontrolled active or severe or atopic dermatitis
- Chronic urticaria
- Eosinophilic esophagitis or other gastrointestinal eosinophilic disorders
- Active malignant neoplasia
- Active systemic, autoimmune disease
- Diabetes treated with insulin
- Severe systemic illness or severe medical conditions such as cardiovascular or lung diseases
- Medication with beta blockers
- Medication with ACE-inhibitors
- Mastocytosis
- Pregnancy or breastfeeding
- Language barriers (not fluent Finnish or Swedish)
The study team makes the final eligibility decision.
Where it's taking place
- Helsinki, Finland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 4 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 1 year to 17 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Helsinki, Finland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.