BridgeMD
New treatment option for Healthy Adults
Official title Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines
ClinicalTrials.gov ID: NCT06929455
What this study is testing
- What it's testing
- Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can keep patients from taking drugs they need for their health.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Between the ages of 18 and 60;
- Generally healthy by self-report;
- All races/ethnicities, both men and women;
- Able to provide informed consent;
- Able to attend repeated visits to Monell for sensory testing;
You likely can't join if
- Under 18 or over 60;
- Pregnant, nursing, or plans to become pregnant;
- Unable to provide consent (including limited ability to understand written and spoken English);
- Tobacco, vape, marijuana, or tetrahydrocannabinol cartridge users. We will accept people who have used tobacco or marijuana products on occasion, but...
- Known drug or food allergies of any kind;
- Diabetes or other metabolic disorder;
See the full eligibility criteria
- Between the ages of 18 and 60;
- Generally healthy by self-report;
- All races/ethnicities, both men and women;
- Able to provide informed consent;
- Able to attend repeated visits to Monell for sensory testing;
- Willing to follow instructions (e.g., refrain from eating or drinking for at least 1 hour before sessions, willing to remain on site for one hour after tasting an API that the participant has never tasted before). -
- Under 18 or over 60;
- Pregnant, nursing, or plans to become pregnant;
- Unable to provide consent (including limited ability to understand written and spoken English);
- Tobacco, vape, marijuana, or tetrahydrocannabinol cartridge users. We will accept people who have used tobacco or marijuana products on occasion, but not regular users;
- Known drug or food allergies of any kind;
- Diabetes or other metabolic disorder;
- Liver issues of any kind, including viral hepatitis;
- Kidney issues of any kind;
- Other chronic illness, including cardiovascular, neurological, immune disorders, or any other serious acute or chronic condition
- Dentures or other major dental implants;
- Condition affecting the oral cavity, including dry mouth, burning mouth syndrome, active sores or blisters, geographic tongue, or other disorders
- Current infection or cold, flu, or infection with SARS-CoV-2 within the last four weeks;
- Unable to taste or smell
- Daily use, or use within the last four weeks, of either prescription or over-the-counter medications (except for birth control)
- History of tuberculosis (including latent tuberculosis), positive skin or other tuberculosis test at any time in the past, birth in or residence in a country with high tuberculosis rates, known contact with someone who...
- HIV infection
The study team makes the final eligibility decision.
Where it's taking place
- Philadelphia, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Philadelphia, Pennsylvania, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.